Entity Details

Primary name ORC1
Entity type gene
Source Source Link

Details

PrimaryID4998
RefseqGeneNG_028251
SymbolORC1
Nameorigin recognition complex subunit 1
Chromosome1
Location1p32.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsORC1_HUMAN

GO terms

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GOName
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000781 chromosome, telomeric region
GO:0000808 origin recognition complex
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003688 DNA replication origin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005664 nuclear origin of replication recognition complex
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0016887 ATP hydrolysis activity
GO:0033314 mitotic DNA replication checkpoint signaling
GO:0036388 pre-replicative complex assembly
GO:0046872 metal ion binding

Diseases

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Interactions

81 interactions

InteractorPartnerSourcesPublicationsLink
ORC1CDC6BioGRID, HPRD, IntAct12614612 12912926 15232106 9566895 details
ORC1CDC5LBioGRID, HPRD, IntAct15232106 details
ORC1MCM5BioGRID, HPRD, IntAct15232106 details
ORC1CDT1BioGRID, HPRD, IntAct15232106 details
ORC1ORC5BioGRID, DIP, HPRD, IntAct12614612 15232106 16549788 17716973 22398447 26496610 31160578 details
ORC1ORC2BioGRID, DIP, HPRD, IntAct11323433 11779870 11931757 12614612 15232106 16549788 17716973 20850016 22398447 26496610 31160578 details
ORC1ORC3BioGRID, DIP, HPRD, IntAct15232106 16549788 17716973 22398447 26496610 31160578 details
ORC1CDK2BioGRID, HPRD, IntAct11931757 31160578 details
ORC1SKP2BioGRID, HPRD, IntAct11931757 31160578 details
ORC1TERF2BioGRID, MINT16799465 18761675 31160578 details
ORC1ABL1IntAct17474147 details
ORC1FYNIntAct17474147 details
ORC1TSG101IntAct19549727 details
ORC1ORC4BioGRID, DIP, IntAct12614612 16549788 17716973 26496610 31160578 details
ORC1GOLGA6L9BioGRID, IntAct32296183 details
ORC1HMGA1DIP18234858 details
ORC1CBX5DIP20689044 details
ORC1MCM2BioGRID, HPRD12614612 details
ORC1MCM7BioGRID, HPRD12614612 details
ORC1CDC7BioGRID, HPRD12614612 details
ORC1MCM4BioGRID12614612 details
ORC1MCM6BioGRID12614612 details
ORC1DBF4BioGRID12614612 details
ORC1CDC45BioGRID12614612 details
ORC1RPA2BioGRID12614612 details
ORC1KAT7BioGRID, HPRD10438470 details
ORC1GOLGA2BioGRID25416956 details
ORC1RB1BioGRID21085491 details
ORC1CCNA2BioGRID, IntAct11931757 26186194 26496610 28514442 31160578 details
ORC1UBBIntAct11931757 details
ORC1LRWD1BioGRID, IntAct26496610 31160578 details
ORC1XRCC5BioGRID12393188 31160578 details
ORC1MGMTBioGRID16226712 details
ORC1OBI1BioGRID31160578 details
ORC1XPO1HPRD11716535 details
ORC1CCNA1IntAct11931757 details
ORC1CHMP1BBioGRID, IntAct26496610 details
ORC1CIRBPBioGRID, IntAct26496610 details
ORC1TRIM26BioGRID, IntAct26496610 details
ORC1DIMT1BioGRID, IntAct26496610 details
ORC1HARS2BioGRID, IntAct26496610 details
ORC1MRPL11BioGRID, IntAct26496610 details
ORC1MRPS15BioGRID, IntAct26496610 details
ORC1MRM3BioGRID, IntAct26496610 details
ORC1CDIPTBioGRID, IntAct26496610 details
ORC1POLE3BioGRID, IntAct26496610 details
ORC1PHIPBioGRID, IntAct26496610 details
ORC1SRP72BioGRID, IntAct26496610 details
ORC1EXOSC2BioGRID, IntAct26496610 details
ORC1PHF3BioGRID, IntAct26496610 details
ORC1PHF6BioGRID, IntAct26496610 details
ORC1ELOBBioGRID, IntAct26496610 details
ORC1SCAMP3BioGRID, IntAct26496610 details
ORC1RFC3BioGRID, IntAct26496610 details
ORC1ZNF174BioGRID, IntAct26496610 details
ORC1DOT1LBioGRID, IntAct26496610 details
ORC1LARP7BioGRID, IntAct26496610 details
ORC1ESR1BioGRID, IntAct31527615 details
ORC1ZNF768BioGRID26496610 details
ORC1ESR2BioGRID29509190 details
ORC1MYCBioGRID29467282 details
ORC1H4C1BioGRID30804502 details
ORC1ORC1BioGRID31160578 details
ORC1CUL1BioGRID31160578 details
ORC1CDK1BioGRID31160578 details
ORC1H4C14BioGRID31160578 details
ORC1XRCC6BioGRID31160578 details
ORC1HNRNPMBioGRID31160578 details
ORC1PSME3BioGRID31160578 details
ORC1H2BC21BioGRID31160578 details
ORC1TERF2IPBioGRID31160578 details
ORC1RBM10BioGRID31160578 details
ORC1H2AC20BioGRID31160578 details
ORC1CKS1BBioGRID31160578 details
ORC1NFIL3BioGRID31160578 details
ORC1SKP1BioGRID31160578 details
ORC1TP53BioGRID32807901 details
ORC1CDCA7LIntAct22078878 details
ORC1KDM4CIntAct22078878 details
ORC1CBX4IntAct22078878 details
ORC1VIRMABioGRID29507755 details