Entity Details

Primary name DUOX2
Entity type gene
Source Source Link

Details

PrimaryID50506
RefseqGeneNG_009447
SymbolDUOX2
Namedual oxidase 2
Chromosome15
Location15q21.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-05
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsDUOX2_HUMAN

GO terms

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GOName
GO:0004601 peroxidase activity
GO:0005509 calcium ion binding
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006590 thyroid hormone generation
GO:0006952 defense response
GO:0006979 response to oxidative stress
GO:0009615 response to virus
GO:0009986 cell surface
GO:0016174 NAD(P)H oxidase H2O2-forming activity
GO:0016175 superoxide-generating NAD(P)H oxidase activity
GO:0016324 apical plasma membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0020037 heme binding
GO:0030054 cell junction
GO:0031252 cell leading edge
GO:0042335 cuticle development
GO:0042446 hormone biosynthetic process
GO:0042554 superoxide anion generation
GO:0042744 hydrogen peroxide catabolic process
GO:0043020 NADPH oxidase complex
GO:0045177 apical part of cell
GO:0050665 hydrogen peroxide biosynthetic process
GO:0051591 response to cAMP
GO:0070062 extracellular exosome
GO:0090303 positive regulation of wound healing
GO:0106293 NADH oxidase H202-forming activity
GO:0106294 NADPH oxidase H202-forming activity
GO:2000147 positive regulation of cell motility

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
DUOX2TXNDC11HPRD, UniProt15561711 details
DUOX2DUOXA2UniProt25761904 details
DUOX2BIRC3BioGRID30948266 details
DUOX2CITBioGRID31586073 details
DUOX2INSBioGRID32457219 details
DUOX2STAT1IntAct21321110 details