Entity Details

Primary name SOX18
Entity type gene
Source Source Link

Details

PrimaryID54345
RefseqGeneNG_008095
SymbolSOX18
NameSRY-box transcription factor 18
Chromosome20
Location20q13.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-06-28
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSOX18_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0001701 in utero embryonic development
GO:0001942 hair follicle development
GO:0001944 vasculature development
GO:0001946 lymphangiogenesis
GO:0001947 heart looping
GO:0003151 outflow tract morphogenesis
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006355 regulation of transcription, DNA-templated
GO:0009653 anatomical structure morphogenesis
GO:0022405 hair cycle process
GO:0030154 cell differentiation
GO:0035050 embryonic heart tube development
GO:0043534 blood vessel endothelial cell migration
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048469 cell maturation
GO:0048866 stem cell fate specification
GO:0060214 endocardium formation
GO:0060836 lymphatic endothelial cell differentiation
GO:0060956 endocardial cell differentiation
GO:0061028 establishment of endothelial barrier
GO:0072091 regulation of stem cell proliferation
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
SOX18MECP2BioGRID, IntAct21988832 details
SOX18GKAP1BioGRID, IntAct21988832 details
SOX18MEF2CBioGRID, HPRD11554755 details
SOX18AURKABioGRID28218735 details
SOX18HMGB1HPRD11748221 details
SOX18IL6STIntAct29408481 details