Entity Details

Primary name PSME2
Entity type gene
Source Source Link

Details

PrimaryID5721
RefseqGeneNG_042234
SymbolPSME2
Nameproteasome activator subunit 2
Chromosome14
Location14q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-11-23
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPSME2_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000209 protein polyubiquitination
GO:0000502 proteasome complex
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006521 regulation of cellular amino acid metabolic process
GO:0008537 proteasome activator complex
GO:0010950 positive regulation of endopeptidase activity
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
GO:0016020 membrane
GO:0016579 protein deubiquitination
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035722 interleukin-12-mediated signaling pathway
GO:0036388 pre-replicative complex assembly
GO:0038061 NIK/NF-kappaB signaling
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042802 identical protein binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043488 regulation of mRNA stability
GO:0043687 post-translational protein modification
GO:0050852 T cell receptor signaling pathway
GO:0055085 transmembrane transport
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061133 endopeptidase activator activity
GO:0061136 regulation of proteasomal protein catabolic process
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070062 extracellular exosome
GO:0070498 interleukin-1-mediated signaling pathway
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:2000045 regulation of G1/S transition of mitotic cell cycle

Diseases

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Interactions

79 interactions

InteractorPartnerSourcesPublicationsLink
PSME2PSME2BioGRID, HPRD, IntAct16189514 32296183 9325261 details
PSME2PSME1BioGRID, IntAct16189514 19017543 22863883 22939629 32296183 8663520 9325261 9346951 details
PSME2EPHA2BioGRID, IntAct21988832 details
PSME2MYOD1BioGRID, IntAct21988832 details
PSME2NHLH1BioGRID, IntAct21988832 details
PSME2NAA10BioGRID, MINT23624078 details
PSME2UBL5BioGRID, IntAct32296183 details
PSME2DUSP23BioGRID, IntAct32296183 details
PSME2SDCBPBioGRID, IntAct28514442 32296183 details
PSME2LNX1BioGRID, IntAct32296183 details
PSME2APPBioGRID21832049 details
PSME2IKBKEIntAct17353931 details
PSME2PSMB9BioGRID, IntAct11745344 26186194 28514442 30833792 details
PSME2PSMB7BioGRID, IntAct11745344 26186194 28514442 details
PSME2MGMTBioGRID16226712 details
PSME2PARD3BioGRID18685789 details
PSME2PSMA2BioGRID19193609 22939629 details
PSME2PSMB6BioGRID11745344 details
PSME2PSMA4BioGRID11745344 details
PSME2PSMD6BioGRID11745344 details
PSME2PSMB8BioGRID11745344 details
PSME2PSMB10BioGRID11745344 details
PSME2PSMD14BioGRID17323924 28821611 details
PSME2U2AF2BioGRID26641092 details
PSME2SIRT7BioGRID28655758 details
PSME2CFTRBioGRID, IntAct17110338 29924966 details
PSME2MAPK6BioGRID, IntAct26972000 details
PSME2SEM1BioGRID, MINT24811749 details
PSME2TMCO3BioGRID, IntAct28514442 details
PSME2CDK15BioGRID, IntAct28514442 details
PSME2FGBBioGRID, IntAct28514442 details
PSME2PSMB1BioGRID, IntAct22939629 28514442 details
PSME2PSMB4BioGRID, IntAct26186194 28514442 details
PSME2PSMB3BioGRID, IntAct22939629 28514442 details
PSME2PSMB2BioGRID, IntAct28514442 32723828 details
PSME2PSMA1BioGRID, IntAct22939629 26186194 28514442 29568061 details
PSME2SPPL2BBioGRID, IntAct28514442 details
PSME2RNF26BioGRID, IntAct28514442 details
PSME2FBXO7BioGRID, IntAct28514442 details
PSME2CTRLBioGRID, IntAct26186194 28514442 details
PSME2HSD17B10BioGRID, IntAct29128334 details
PSME2SOD1BioGRID, IntAct29128334 details
PSME2ENGBioGRID, UniProt31540324 details
PSME2SH3BGRLBioGRID, IntAct31980649 details
PSME2ZDHHC5UniProt31402609 details
PSME2PSMC5BioGRID22939629 details
PSME2PSMC2BioGRID22939629 details
PSME2PSMA5BioGRID22939629 details
PSME2PSMA6BioGRID22939629 details
PSME2PSMA3BioGRID22939629 30009671 details
PSME2PSMD7BioGRID22939629 details
PSME2PSMC1BioGRID22939629 details
PSME2PSMD2BioGRID22939629 details
PSME2PSMC4BioGRID22939629 details
PSME2PSMB5BioGRID22939629 details
PSME2PSMD1BioGRID22939629 details
PSME2CAP1BioGRID22939629 details
PSME2PTMABioGRID22939629 details
PSME2GARS1BioGRID22939629 details
PSME2DDTLBioGRID22939629 details
PSME2TNNBioGRID22939629 details
PSME2PRKNBioGRID23503661 details
PSME2BAG3BioGRID23824909 details
PSME2NTRK1BioGRID25921289 details
PSME2MCM2BioGRID25963833 details
PSME2CCND2BioGRID27371349 details
PSME2MTCH2BioGRID27684187 details
PSME2PRPF8BioGRID28515276 details
PSME2EFTUD2BioGRID28515276 details
PSME2AAR2BioGRID28515276 details
PSME2PIH1D1BioGRID28515276 details
PSME2RECQL4BioGRID29229926 details
PSME2VIRMABioGRID29507755 details
PSME2ARNTLBioGRID29871923 details
PSME2CLUAP1BioGRID29615496 details
PSME2WWP2BioGRID31048545 details
PSME2CITBioGRID31586073 details
PSME2BRD4BioGRID32416067 details
PSME2RPL31BioGRID34079125 details