Entity Details

Primary name SORT1
Entity type gene
Source Source Link

Details

PrimaryID6272
RefseqGeneNG_028280
SymbolSORT1
Namesortilin 1
Chromosome1
Location1p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-11-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSORT_HUMAN

GO terms

Show/Hide Table
GOName
GO:0001503 ossification
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005769 early endosome
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005905 clathrin-coated pit
GO:0006622 protein targeting to lysosome
GO:0006892 post-Golgi vesicle-mediated transport
GO:0006895 Golgi to endosome transport
GO:0006897 endocytosis
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007275 multicellular organism development
GO:0008333 endosome to lysosome transport
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0009986 cell surface
GO:0010008 endosome membrane
GO:0010465 nerve growth factor receptor activity
GO:0010468 regulation of gene expression
GO:0014902 myotube differentiation
GO:0016021 integral component of membrane
GO:0016050 vesicle organization
GO:0019899 enzyme binding
GO:0030136 clathrin-coated vesicle
GO:0030140 trans-Golgi network transport vesicle
GO:0030379 neurotensin receptor activity, non-G protein-coupled
GO:0030425 dendrite
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0031965 nuclear membrane
GO:0032509 endosome transport via multivesicular body sorting pathway
GO:0032580 Golgi cisterna membrane
GO:0032868 response to insulin
GO:0043025 neuronal cell body
GO:0045599 negative regulation of fat cell differentiation
GO:0046323 glucose import
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048227 plasma membrane to endosome transport
GO:0048406 nerve growth factor binding
GO:0048471 perinuclear region of cytoplasm
GO:0051005 negative regulation of lipoprotein lipase activity
GO:0090160 Golgi to lysosome transport
GO:1904037 positive regulation of epithelial cell apoptotic process
GO:1905394 retromer complex binding

Diseases

Show/Hide Table

Interactions

165 interactions

InteractorPartnerSourcesPublicationsLink
SORT1GGA2BioGRID, HPRD, MINT11331584 11390366 11821067 details
SORT1GGA1BioGRID, HPRD, I2D, MINT11390366 11821067 11859376 20015111 20676133 details
SORT1GRNDIP, MINT23236149 24070898 details
SORT1LRPAP1bhf-ucl, BioGRID, DIP, HPRD, IntAct10085125 18687776 19122660 20584990 9013611 9927419 details
SORT1LPLbhf-ucl10085125 details
SORT1NGFbhf-ucl, BioGRID, DIP, HPRD14985763 19122660 20159974 details
SORT1NTSbhf-ucl, BioGRID, HPRD, IntAct14985763 16087676 21261755 24128306 9756851 details
SORT1NTRK3bhf-ucl, BioGRID21102451 details
SORT1NTRK1bhf-ucl, BioGRID21102451 25921289 details
SORT1NTRK2bhf-ucl, BioGRID21102451 details
SORT1FAM3CIntAct32296183 details
SORT1VAMP5IntAct32296183 details
SORT1BRICD5BioGRID, IntAct32296183 details
SORT1CNIH3BioGRID, IntAct32296183 details
SORT1TFBioGRID, IntAct32296183 details
SORT1BDNFBioGRID, DIP, HPRD, IntAct15987945 19122660 20159974 21357693 32296183 details
SORT1ADGRG7BioGRID, IntAct32296183 details
SORT1SORT1DIP19122660 details
SORT1CNTFIntAct20584990 details
SORT1CTF1IntAct20584990 details
SORT1LIFIntAct20584990 details
SORT1OSMIntAct20584990 details
SORT1LIFRIntAct20584990 details
SORT1IL6IntAct25401472 details
SORT1SORCS1BioGRID, IntAct12482870 24128306 details
SORT1GLAIntAct21949853 details
SORT1TGIntAct18687776 details
SORT1VPS29IntAct32814053 details
SORT1SORL1BioGRID11294867 details
SORT1NTF3BioGRID21261755 details
SORT1NGFRbhf-ucl, BioGRID, HPRD14985763 20159974 21261755 details
SORT1APPUniProt23283322 details
SORT1GGA3BioGRID11390366 details
SORT1STAMBioGRID11390366 details
SORT1BACE1BioGRID21245145 details
SORT1HAP1BioGRID21357693 details
SORT1CDK2BioGRID, IntAct17353931 26496610 details
SORT1NUDCD3BioGRID, IntAct25036637 details
SORT1FOXR1BioGRID, MINT25609649 details
SORT1IRF3BioGRID, MINT25609649 details
SORT1PHC2BioGRID, IntAct26496610 details
SORT1MRPL55BioGRID, IntAct26496610 details
SORT1XRCC2BioGRID, IntAct26496610 details
SORT1ABCA7BioGRID, IntAct26496610 details
SORT1SLC25A25BioGRID, IntAct26496610 details
SORT1DDX51BioGRID, IntAct26496610 details
SORT1KRT75BioGRID, IntAct26496610 details
SORT1TXNDC11BioGRID, IntAct26496610 details
SORT1TUBA1CBioGRID, IntAct26496610 details
SORT1PARP9BioGRID, IntAct26496610 details
SORT1SBF2BioGRID, IntAct26496610 details
SORT1C2CD5BioGRID, IntAct26496610 details
SORT1NOL6BioGRID, IntAct26496610 details
SORT1TMEM9BioGRID, IntAct26496610 details
SORT1LAMTOR5BioGRID, IntAct26496610 details
SORT1EME1BioGRID, IntAct26496610 details
SORT1NDUFB5BioGRID, IntAct26496610 details
SORT1BAIAP2L1BioGRID, IntAct26496610 details
SORT1TRIOBPBioGRID, IntAct26496610 details
SORT1RAB11FIP5BioGRID, IntAct26496610 details
SORT1CSNK1G2BioGRID, IntAct26496610 details
SORT1NHSBioGRID, IntAct26496610 details
SORT1FNDC3ABioGRID, IntAct26496610 details
SORT1LMTK2BioGRID, IntAct26496610 details
SORT1GPBP1BioGRID, IntAct26496610 details
SORT1MORC2BioGRID, IntAct26496610 details
SORT1RRP1BBioGRID, IntAct26496610 details
SORT1UACABioGRID, IntAct26496610 details
SORT1CENPVBioGRID, IntAct26496610 details
SORT1MYH1BioGRID, IntAct26496610 details
SORT1C2orf69BioGRID, IntAct26496610 details
SORT1XIAPBioGRID, IntAct26496610 details
SORT1USP1BioGRID, IntAct26496610 details
SORT1PEAK1BioGRID, IntAct26496610 details
SORT1BADBioGRID, IntAct26496610 details
SORT1CDK1BioGRID, IntAct26496610 details
SORT1UGGT2BioGRID, IntAct26496610 details
SORT1WWP2BioGRID, IntAct26496610 details
SORT1PALMDBioGRID, IntAct26496610 details
SORT1SYNCRIPBioGRID, IntAct26496610 details
SORT1UAP1BioGRID, IntAct26496610 details
SORT1RBM28BioGRID, IntAct26496610 details
SORT1SPTBN2BioGRID, IntAct26496610 details
SORT1UPF1BioGRID, IntAct26496610 details
SORT1DNAJA4BioGRID, IntAct26496610 details
SORT1OASLBioGRID, IntAct26496610 details
SORT1UTP15BioGRID, IntAct26496610 details
SORT1FBXL19BioGRID, IntAct26496610 details
SORT1BLMHBioGRID, IntAct26496610 details
SORT1TUBBBioGRID, IntAct26496610 details
SORT1HPBioGRID, IntAct26496610 details
SORT1NOP2BioGRID, IntAct26496610 details
SORT1DIS3BioGRID, IntAct26496610 details
SORT1BRIX1BioGRID, IntAct26496610 details
SORT1URB1BioGRID, IntAct26496610 details
SORT1NSMCE2BioGRID, IntAct26496610 details
SORT1YBX1BioGRID, IntAct26496610 details
SORT1USP15BioGRID, IntAct26496610 details
SORT1COPABioGRID, IntAct26496610 details
SORT1ARHGAP32BioGRID, IntAct26496610 details
SORT1MRPL24BioGRID, IntAct26496610 details
SORT1SIRT5BioGRID, IntAct26496610 details
SORT1DDX60BioGRID, IntAct26496610 details
SORT1TECBioGRID, IntAct26496610 details
SORT1GOLGA3BioGRID, IntAct26496610 details
SORT1TSEN2BioGRID, IntAct26496610 details
SORT1RETBioGRID, IntAct26496610 details
SORT1LEMD2BioGRID, IntAct26496610 details
SORT1MRM1BioGRID, IntAct26496610 details
SORT1TCOF1BioGRID, IntAct26496610 details
SORT1HSD17B4BioGRID, IntAct26496610 details
SORT1ICE2BioGRID, IntAct26496610 details
SORT1PDE12BioGRID, IntAct26496610 details
SORT1URB2BioGRID, IntAct26496610 details
SORT1EIF2B1BioGRID, IntAct26496610 details
SORT1ASS1BioGRID, IntAct26496610 details
SORT1SH3PXD2BBioGRID, IntAct26496610 details
SORT1KLHDC2BioGRID, IntAct26496610 details
SORT1RAB13BioGRID, IntAct26496610 details
SORT1COBLL1BioGRID, IntAct26496610 details
SORT1FAF2BioGRID, IntAct26496610 details
SORT1PLCB3BioGRID, IntAct26496610 details
SORT1DICER1BioGRID, IntAct26496610 details
SORT1PRCCBioGRID, IntAct26496610 details
SORT1FANCMBioGRID, IntAct26496610 details
SORT1MYH6BioGRID, IntAct26496610 details
SORT1CSPG4BioGRID, IntAct26496610 details
SORT1GTF2IRD1BioGRID, IntAct26496610 details
SORT1PI4KABioGRID, IntAct26496610 details
SORT1MIA3BioGRID, IntAct26496610 details
SORT1MED13LBioGRID, IntAct26496610 details
SORT1YARS1BioGRID, IntAct26496610 details
SORT1SSH3BioGRID, IntAct26496610 details
SORT1LSM14ABioGRID, IntAct26496610 details
SORT1USP32BioGRID, IntAct26496610 details
SORT1TLN1BioGRID, IntAct26496610 details
SORT1ICAM5BioGRID, IntAct26496610 details
SORT1IPO9BioGRID, IntAct26496610 details
SORT1APTXBioGRID, IntAct26496610 details
SORT1BIN3BioGRID, IntAct26496610 details
SORT1UFSP2BioGRID, IntAct26496610 details
SORT1TCIRG1BioGRID, IntAct26496610 details
SORT1KIAA1191BioGRID, IntAct26496610 details
SORT1SSR1BioGRID, IntAct26496610 details
SORT1P2RY6BioGRID, IntAct30833792 details
SORT1NSD2BioGRID, MINT24981860 details
SORT1APBB2BioGRID26496610 details
SORT1KLC1BioGRID26496610 details
SORT1MAP3K4BioGRID26496610 details
SORT1SRSF2BioGRID26496610 details
SORT1USP11BioGRID26496610 details
SORT1MPHOSPH6BioGRID26496610 details
SORT1ZC3HAV1BioGRID26496610 details
SORT1TENT4BBioGRID26496610 details
SORT1ZNF768BioGRID26496610 details
SORT1MUS81BioGRID26496610 details
SORT1CDRT4BioGRID26496610 details
SORT1PTPRN2BioGRID27880917 details
SORT1EGLN3BioGRID26972000 details
SORT1ESR2BioGRID29509190 details
SORT1LMBR1LBioGRID31073040 details
SORT1MARCHF4BioGRID32614325 details
SORT1MARCHF6BioGRID32614325 details
SORT1ELAVL1BioGRID19322201 details
SORT1VIRMABioGRID29507755 details