Entity Details

Primary name XCL1
Entity type gene
Source Source Link

Details

PrimaryID6375
RefseqGene
SymbolXCL1
NameX-C motif chemokine ligand 1
Chromosome1
Location1q24.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-17
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsXCL1_HUMAN

GO terms

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GOName
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002548 monocyte chemotaxis
GO:0002690 positive regulation of leukocyte chemotaxis
GO:0002725 negative regulation of T cell cytokine production
GO:0002726 positive regulation of T cell cytokine production
GO:0002826 negative regulation of T-helper 1 type immune response
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008009 chemokine activity
GO:0009615 response to virus
GO:0010820 positive regulation of T cell chemotaxis
GO:0030593 neutrophil chemotaxis
GO:0031640 killing of cells of other organism
GO:0032689 negative regulation of interferon-gamma production
GO:0032703 negative regulation of interleukin-2 production
GO:0032733 positive regulation of interleukin-10 production
GO:0035782 mature natural killer cell chemotaxis
GO:0042379 chemokine receptor binding
GO:0042803 protein homodimerization activity
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043547 positive regulation of GTPase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048020 CCR chemokine receptor binding
GO:0048247 lymphocyte chemotaxis
GO:0050727 regulation of inflammatory response
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070098 chemokine-mediated signaling pathway
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071353 cellular response to interleukin-4
GO:0071356 cellular response to tumor necrosis factor
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0071636 positive regulation of transforming growth factor beta production
GO:0071663 positive regulation of granzyme B production
GO:0090023 positive regulation of neutrophil chemotaxis
GO:2000412 positive regulation of thymocyte migration
GO:2000503 positive regulation of natural killer cell chemotaxis
GO:2000513 positive regulation of granzyme A production
GO:2000518 negative regulation of T-helper 1 cell activation
GO:2000538 positive regulation of B cell chemotaxis
GO:2000553 positive regulation of T-helper 2 cell cytokine production
GO:2000556 positive regulation of T-helper 1 cell cytokine production
GO:2000558 positive regulation of immunoglobulin production in mucosal tissue
GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation
GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation
GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation

Diseases

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Interactions

55 interactions

InteractorPartnerSourcesPublicationsLink
XCL1XCL1DIP, HPRD11601972 18364395 details
XCL1CCL5bhf-ucl, BioGRID28381538 details
XCL1PF4bhf-ucl, BioGRID28381538 details
XCL1CXCL12bhf-ucl, BioGRID28381538 details
XCL1CCL13bhf-ucl, BioGRID28381538 details
XCL1CCL11bhf-ucl, BioGRID28381538 details
XCL1CCL21bhf-ucl, BioGRID28381538 details
XCL1CCL24bhf-ucl, BioGRID28381538 details
XCL1CXCL11bhf-ucl, BioGRID28381538 details
XCL1CXCL9bhf-ucl, BioGRID28381538 details
XCL1PF4V1bhf-ucl, BioGRID28381538 details
XCL1CCL26bhf-ucl, BioGRID28381538 details
XCL1CCL28bhf-ucl, BioGRID28381538 details
XCL1CXCL14bhf-ucl, BioGRID28381538 details
XCL1CXCL2bhf-ucl, BioGRID28381538 details
XCL1CXCL10bhf-ucl, BioGRID28381538 details
XCL1CXCL17bhf-ucl, BioGRID28381538 details
XCL1KRTAP10-3BioGRID25416956 details
XCL1XCR1HPRD11446740 9632725 details
XCL1VCANHPRD11083865 details
XCL1ADGRV1BioGRID, IntAct28514442 details
XCL1FAT3BioGRID, IntAct28514442 details
XCL1FAT4BioGRID, IntAct28514442 details
XCL1TUBB8BioGRID, IntAct28514442 details
XCL1TUBB3BioGRID, IntAct28514442 details
XCL1FSTL1BioGRID, IntAct28514442 details
XCL1COL6A2BioGRID, IntAct28514442 details
XCL1TFECIntAct33179750 details
XCL1TBXTIntAct33179750 details
XCL1TBX22IntAct33179750 details
XCL1TBX20IntAct33179750 details
XCL1TBX19IntAct33179750 details
XCL1SMAD4IntAct33179750 details
XCL1RXRGIntAct33179750 details
XCL1RUNX3IntAct33179750 details
XCL1RUNX1IntAct33179750 details
XCL1NR2F6IntAct33179750 details
XCL1NR2F2IntAct33179750 details
XCL1NR2F1IntAct33179750 details
XCL1NR2C2IntAct33179750 details
XCL1MSCIntAct33179750 details
XCL1MITFIntAct33179750 details
XCL1MEIS2IntAct33179750 details
XCL1MEIS1IntAct33179750 details
XCL1MAXIntAct33179750 details
XCL1IRX6IntAct33179750 details
XCL1HEY2IntAct33179750 details
XCL1ETV3IntAct33179750 details
XCL1EBF3IntAct33179750 details
XCL1BNC1IntAct33179750 details
XCL1TGIF1IntAct33179750 details
XCL1ZIC1IntAct33179750 details
XCL1USF2IntAct33179750 details
XCL1USF1IntAct33179750 details
XCL1TGIF2LXIntAct33179750 details