Entity Details

Primary name TKFC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ3LXA3
EntryNameTKFC_HUMAN
FullNameTriokinase/FMN cyclase
TaxID9606
Evidenceevidence at protein level
Length575
SequenceStatuscomplete
DateCreated2006-01-24
DateModified2021-06-02

Ontological Relatives

GenesTKFC

GO terms

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GOName
GO:0004371 glycerone kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005829 cytosol
GO:0019563 glycerol catabolic process
GO:0034012 FAD-AMP lyase (cyclizing) activity
GO:0039534 negative regulation of MDA-5 signaling pathway
GO:0044262 cellular carbohydrate metabolic process
GO:0045087 innate immune response
GO:0045088 regulation of innate immune response
GO:0046835 carbohydrate phosphorylation
GO:0046872 metal ion binding
GO:0050354 triokinase activity
GO:0061624 fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
GO:0070062 extracellular exosome

Subcellular Location

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Domains

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DomainNameCategoryType
IPR004006 DhaK domainDomainDomain
IPR004007 DhaL domainDomainDomain
IPR012734 Dihydroxyacetone kinaseFamilyFamily
IPR036117 DhaL domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
TKFC_HUMANSDCB1_HUMANBioGRID, IntAct25416956 details
TKFC_HUMANIFIH1_HUMANDIP17600090 details
TKFC_HUMANTKFC_HUMANBioGRID24569995 details