Entity Details

Primary name SOX4
Entity type gene
Source Source Link

Details

PrimaryID6659
RefseqGeneNG_029166
SymbolSOX4
NameSRY-box transcription factor 4
Chromosome6
Location6p22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSOX4_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001501 skeletal system development
GO:0001841 neural tube formation
GO:0002328 pro-B cell differentiation
GO:0003183 mitral valve morphogenesis
GO:0003211 cardiac ventricle formation
GO:0003215 cardiac right ventricle morphogenesis
GO:0003289 atrial septum primum morphogenesis
GO:0003357 noradrenergic neuron differentiation
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0006355 regulation of transcription, DNA-templated
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007507 heart development
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0009653 anatomical structure morphogenesis
GO:0014009 glial cell proliferation
GO:0021510 spinal cord development
GO:0021522 spinal cord motor neuron differentiation
GO:0021782 glial cell development
GO:0030154 cell differentiation
GO:0030217 T cell differentiation
GO:0031018 endocrine pancreas development
GO:0031397 negative regulation of protein ubiquitination
GO:0031647 regulation of protein stability
GO:0032024 positive regulation of insulin secretion
GO:0035019 somatic stem cell population maintenance
GO:0035198 miRNA binding
GO:0035910 ascending aorta morphogenesis
GO:0042593 glucose homeostasis
GO:0042769 DNA damage response, detection of DNA damage
GO:0043065 positive regulation of apoptotic process
GO:0045588 positive regulation of gamma-delta T cell differentiation
GO:0045727 positive regulation of translation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048485 sympathetic nervous system development
GO:0050821 protein stabilization
GO:0060174 limb bud formation
GO:0060412 ventricular septum morphogenesis
GO:0060548 negative regulation of cell death
GO:0060563 neuroepithelial cell differentiation
GO:0060993 kidney morphogenesis
GO:0061484 hematopoietic stem cell homeostasis
GO:0071333 cellular response to glucose stimulus
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation

Diseases

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Interactions

51 interactions

InteractorPartnerSourcesPublicationsLink
SOX4TP53BioGRID, DIP19234109 details
SOX4SDCBPBioGRID, HPRD11498591 details
SOX4UBE2IBioGRID, HPRD16631117 details
SOX4TNNI3BioGRID25969425 details
SOX4SCNN1GBioGRID25969425 details
SOX4MINPP1BioGRID25969425 details
SOX4IGF1BioGRID25969425 details
SOX4PLD3BioGRID25969425 details
SOX4CAPN15BioGRID25969425 details
SOX4FOXH1BioGRID25969425 details
SOX4RGSL1BioGRID25969425 details
SOX4LMNB2BioGRID25969425 details
SOX4CTR9BioGRID25969425 details
SOX4ITIH1BioGRID25969425 details
SOX4APOC3BioGRID25969425 details
SOX4EDF1BioGRID25969425 details
SOX4NANOGNBBioGRID25969425 details
SOX4MNTBioGRID25969425 details
SOX4PLXNB1BioGRID25969425 details
SOX4RP1L1BioGRID25969425 details
SOX4BANF1BioGRID25969425 details
SOX4RHOUBioGRID26598620 details
SOX4AURKABioGRID28205554 details
SOX4CDKN2ABioGRID28205554 details
SOX4DACH1BioGRID28205554 details
SOX4NSD3BioGRID28205554 details
SOX4AKT1BioGRID28205554 details
SOX4FZR1BioGRID28205554 details
SOX4KRASBioGRID28205554 details
SOX4MYCBioGRID28205554 details
SOX4NF1BioGRID28205554 details
SOX4NF2BioGRID28205554 details
SOX4SMARCA4BioGRID28205554 details
SOX4STK11BioGRID28205554 details
SOX4TERTBioGRID28205554 details
SOX4TSC1BioGRID28205554 details
SOX4WT1BioGRID28205554 details
SOX4GATA3InnateDB22751141 details
SOX4EPS15L1BioGRID, IntAct27173435 unassigned1312 details
SOX4USP15BioGRID, IntAct27173435 unassigned1312 details
SOX4MCM2BioGRID, IntAct27173435 unassigned1312 details
SOX4MCM4BioGRID, IntAct27173435 unassigned1312 details
SOX4SPAG9BioGRID, IntAct27173435 unassigned1312 details
SOX4MCM6BioGRID, IntAct27173435 unassigned1312 details
SOX4EP300BioGRID, DIP19234109 details
SOX4CREBBPDIP19234109 details
SOX4MDM2BioGRID19234109 details
SOX4TAF5BioGRID23884650 details
SOX4JUNDIntAct23482931 details
SOX4FOSL2IntAct23482931 details
SOX4ELAVL1BioGRID19322201 details