Entity Details

Primary name CRFM7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ494W8
EntryNameCRFM7_HUMAN
FullNameCHRNA7-FAM7A fusion protein
TaxID9606
Evidenceevidence at protein level
Length412
SequenceStatuscomplete
DateCreated2006-04-04
DateModified2021-06-02

Ontological Relatives

GenesCHRFAM7A

GO terms

Show/Hide Table
GOName
GO:0004888 transmembrane signaling receptor activity
GO:0005230 extracellular ligand-gated ion channel activity
GO:0005887 integral component of plasma membrane
GO:0005892 acetylcholine-gated channel complex
GO:0007165 signal transduction
GO:0007268 chemical synaptic transmission
GO:0007271 synaptic transmission, cholinergic
GO:0030594 neurotransmitter receptor activity
GO:0034220 ion transmembrane transport
GO:0042166 acetylcholine binding
GO:0042391 regulation of membrane potential
GO:0043005 neuron projection
GO:0045202 synapse
GO:0050877 nervous system process

Subcellular Location

Show/Hide Table
Subcellular Location
Membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB07494 (3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANEDrugbanksmall molecule
DB07720 EpibatidineDrugbanksmall molecule
DB08620 ThiaclopridDrugbanksmall molecule
DB11421 ImidaclopridDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CRFM7_HUMANACHA7_HUMANUniProt28750690 details