Entity Details

Primary name PIF1
Entity type gene
Source Source Link

Details

PrimaryID80119
RefseqGene
SymbolPIF1
NamePIF1 5'-to-3' DNA helicase
Chromosome15
Location15q22.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPIF1_HUMAN

GO terms

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GOName
GO:0000002 mitochondrial genome maintenance
GO:0000287 magnesium ion binding
GO:0000781 chromosome, telomeric region
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005657 replication fork
GO:0005739 mitochondrion
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0007004 telomere maintenance via telomerase
GO:0010521 telomerase inhibitor activity
GO:0017116 single-stranded DNA helicase activity
GO:0032204 regulation of telomere maintenance
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0032508 DNA duplex unwinding
GO:0033678 5'-3' DNA/RNA helicase activity
GO:0042162 telomeric DNA binding
GO:0043139 5'-3' DNA helicase activity
GO:0051880 G-quadruplex DNA binding
GO:0051974 negative regulation of telomerase activity

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
PIF1HSF2IntAct25036637 details
PIF1ZNRD2BioGRID, IntAct28514442 details
PIF1HNRNPH1BioGRID26760575 details