Entity Details

Primary name CARD11
Entity type gene
Source Source Link

Details

PrimaryID84433
RefseqGeneNG_027759
SymbolCARD11
Namecaspase recruitment domain family member 11
Chromosome7
Location7p22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCAR11_HUMAN

GO terms

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GOName
GO:0001772 immunological synapse
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0004385 guanylate kinase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0030183 B cell differentiation
GO:0030890 positive regulation of B cell proliferation
GO:0031295 T cell costimulation
GO:0032449 CBM complex
GO:0032743 positive regulation of interleukin-2 production
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0038202 TORC1 signaling
GO:0042100 B cell proliferation
GO:0042102 positive regulation of T cell proliferation
GO:0042981 regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045061 thymic T cell selection
GO:0045121 membrane raft
GO:0045577 regulation of B cell differentiation
GO:0045580 regulation of T cell differentiation
GO:0048872 homeostasis of number of cells
GO:0050700 CARD domain binding
GO:0050852 T cell receptor signaling pathway
GO:0050862 positive regulation of T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070062 extracellular exosome

Diseases

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Interactions

36 interactions

InteractorPartnerSourcesPublicationsLink
CARD11IKBKGBioGRID, HPRD, MINT15184390 16301747 17363905 18625728 details
CARD11BCL10BioGRID, DIP, HPRD, IntAct, MINT11278692 11356195 16356855 17948050 18625728 18806265 19118383 19444310 19815501 21157432 21513986 22528498 23690623 24074955 25548215 27777308 30279415 details
CARD11TAB1BioGRID, MINT21900206 details
CARD11PDPK1BioGRID, HPRD, MINT15802604 21900206 details
CARD11AKT1IntAct24548923 details
CARD11PRKCQBioGRID, HPRD, IntAct14673152 16356855 19706536 20164171 21157432 22528498 details
CARD11MAP4K1BioGRID, DIP19706536 details
CARD11PRKCBBioGRID, HPRD16356855 details
CARD11SRPK2BioGRID26167880 details
CARD11RNF181BioGRID26711259 details
CARD11PPP2R1ABioGRID21157432 details
CARD11PPP2CABioGRID21157432 details
CARD11MALT1BioGRID, IntAct, MINT17948050 22528498 23322406 25748427 31961340 33329596 details
CARD11COPS5BioGRID, MINT19444310 details
CARD11GPS1BioGRID, MINT19444310 details
CARD11PRKCDBioGRID, IntAct22528498 details
CARD11CSNK1A1BioGRID, DIP19118383 25088585 details
CARD11CBLBBioGRID, DIP19815501 details
CARD11MAP3K7BioGRID, HPRD16301747 18625728 20164171 27497262 details
CARD11FYB1BioGRID20164171 details
CARD11DPP4BioGRID17287217 details
CARD11CARD11BioGRID18625728 details
CARD11TRAF6BioGRID18625728 details
CARD11CASP8BioGRID18625728 details
CARD11CHUKBioGRID16356855 18625728 details
CARD11STUB1BioGRID23322406 details
CARD11CCND1BioGRID23322406 details
CARD11USP2BioGRID23264041 details
CARD11USP18BioGRID23825189 details
CARD11RNF31BioGRID27777308 33329596 details
CARD11TAB3BioGRID27497262 details
CARD11RBCK1BioGRID33329596 details
CARD11ZAP70HPRD12154360 details
CARD11SH2D3CHPRD16825666 details
CARD11WDR1HPRD17293856 details
CARD11TRIM37BioGRID33194618 details