Entity Details

Primary name NCOA1
Entity type gene
Source Source Link

Details

PrimaryID8648
RefseqGeneNG_029014
SymbolNCOA1
Namenuclear receptor coactivator 1
Chromosome2
Location2p23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNCOA1_HUMAN

GO terms

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GOName
GO:0000435 positive regulation of transcription from RNA polymerase II promoter by galactose
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0002155 regulation of thyroid hormone mediated signaling pathway
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0004402 histone acetyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007595 lactation
GO:0008584 male gonad development
GO:0015721 bile acid and bile salt transport
GO:0016922 nuclear receptor binding
GO:0017162 aryl hydrocarbon receptor binding
GO:0019216 regulation of lipid metabolic process
GO:0019899 enzyme binding
GO:0021549 cerebellum development
GO:0021766 hippocampus development
GO:0021854 hypothalamus development
GO:0021987 cerebral cortex development
GO:0030331 estrogen receptor binding
GO:0030374 nuclear receptor coactivator activity
GO:0030522 intracellular receptor signaling pathway
GO:0032355 response to estradiol
GO:0032526 response to retinoic acid
GO:0032570 response to progesterone
GO:0032870 cellular response to hormone stimulus
GO:0032991 protein-containing complex
GO:0033142 progesterone receptor binding
GO:0043005 neuron projection
GO:0043065 positive regulation of apoptotic process
GO:0043967 histone H4 acetylation
GO:0044849 estrous cycle
GO:0044877 protein-containing complex binding
GO:0045666 positive regulation of neuron differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045925 positive regulation of female receptivity
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046965 retinoid X receptor binding
GO:0046983 protein dimerization activity
GO:0047485 protein N-terminus binding
GO:0060179 male mating behavior
GO:0060713 labyrinthine layer morphogenesis
GO:1904017 cellular response to Thyroglobulin triiodothyronine
GO:2001038 regulation of cellular response to drug

Diseases

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Interactions

123 interactions

InteractorPartnerSourcesPublicationsLink
NCOA1CREBBPBioGRID, HPRD, MINT, UniProt11003650 11113179 11971985 12163591 12482968 14722092 15615775 16860316 8616895 9192892 9445475 details
NCOA1RARABioGRID, DIP, HPRD, MINT, UniProt10082574 10454579 10760302 12138096 12665583 16456540 16606617 17363140 17475621 17641689 20338915 20543827 21478865 23975195 9121466 9192892 details
NCOA1PSMB9HPRD, MINT16957778 details
NCOA1ESR1BioGRID, HPRD, IntAct, MINT, UniProt10454579 10598586 10731636 10760302 11003650 11014206 11113179 11165056 11358671 11376110 11682626 11867769 12554772 12574227 12630920 12714702 12738788 14715875 15140878 15604093 16282588 16606617 16957778 17363140 17627277 20608937 23874500 23975195 26487511 9121466 9192892 9192902 9259327 9427757 9773983 9774463 details
NCOA1ARBioGRID, HPRD, IntAct10567563 10731636 12163482 12612084 15256534 17353003 23975195 details
NCOA1NCOA3BioGRID, MINT17476305 18267973 details
NCOA1GRIP1MINT17476305 details
NCOA1KANK2BioGRID, MINT17476305 details
NCOA1RXRABioGRID, DIP, HPRD, IntAct, MINT10082574 10454579 10517671 10935544 11027271 11124027 11438648 12612084 15140878 17363140 17673910 20682316 21478865 23602807 23975195 7481822 9121466 9171239 details
NCOA1PAGR1BioGRID, MINT19039327 details
NCOA1NR1H3BioGRID, MINT15604093 20682316 25962847 details
NCOA1NR3C1BioGRID, HPRD, UniProt10659697 10731636 11266503 12118039 12569182 12917342 16423881 16606617 28611094 31182584 9590696 details
NCOA1SNW1BioGRID, UniProt14985122 details
NCOA1RORCIntAct20203100 details
NCOA1RORABioGRID, IntAct15604093 20203100 23975195 details
NCOA1ESR2BioGRID, HPRD, IntAct10731636 10809226 11014206 11376110 11500849 12554772 14715875 15604093 19126643 details
NCOA1NR1H4BioGRID, DIP, HPRD, UniProt11136553 14684751 14698205 18391212 20338915 details
NCOA1TRIM27BioGRID, IntAct32296183 details
NCOA1NR1I2BioGRID, HPRD, IntAct12072427 12909012 15331348 15604093 16455805 17429319 18096694 19171678 23160820 23602807 details
NCOA1PPARABioGRID, IntAct10731636 12163133 15888456 21775429 9407140 9626662 details
NCOA1PPARDBioGRID, IntAct15001550 15604093 15888456 16930961 21775429 details
NCOA1NR1I3BioGRID, HPRD, IntAct15572376 15604093 26186194 28514442 details
NCOA1VDRBioGRID, DIP, HPRD, IntAct10224118 11075811 11124027 11149488 12403843 12612084 12796488 15604093 17786964 21478865 23975195 9121466 9878542 details
NCOA1NR5A2BioGRID, DIP15604093 22504882 23975195 details
NCOA1ESRRABioGRID, HPRD, IntAct11165056 15337744 15604093 23975195 details
NCOA1PGRBioGRID, HPRD, IntAct10722692 10757795 12529333 16282588 16352595 16728408 21273440 29202468 7481822 details
NCOA1FOSBioGRID, HPRD10847592 18511550 9642216 details
NCOA1JUNBioGRID, HPRD10567404 10847592 9642216 details
NCOA1NFKB1BioGRID, HPRD10847592 9556555 details
NCOA1CIITABioGRID, HPRD12933903 details
NCOA1SMARCE1BioGRID, HPRD12145209 16538531 17363140 details
NCOA1BCL3BioGRID, HPRD10497212 details
NCOA1YWHAQBioGRID11266503 details
NCOA1STAT6BioGRID, HPRD11574547 12138096 14757047 14993689 15695802 18267973 details
NCOA1TRIP4BioGRID, HPRD10454579 details
NCOA1KAT2BBioGRID, HPRD9223281 9296499 9445475 details
NCOA1PRMT1BioGRID, HPRD11050077 details
NCOA1NR4A1BioGRID, HPRD12082103 16002533 details
NCOA1NCOR1BioGRID12569182 details
NCOA1FOXA2BioGRID, HPRD11069927 details
NCOA1RARBBioGRID, HPRD12665583 15604093 17363140 8754792 details
NCOA1GTF2BBioGRID, HPRD8754792 details
NCOA1TBPBioGRID, HPRD8754792 details
NCOA1TEAD2BioGRID, HPRD10934189 details
NCOA1TEAD1BioGRID10934189 details
NCOA1STAT3BioGRID, HPRD11773079 17471507 details
NCOA1HNF4ABioGRID, HPRD9812974 details
NCOA1HIF1ABioGRID, HPRD10594042 details
NCOA1NR5A1BioGRID, HPRD9328345 details
NCOA1CCND1BioGRID, HPRD9832502 details
NCOA1ESRRGBioGRID, HPRD11864604 15604093 details
NCOA1THRBBioGRID, HPRD10454579 11435616 12612084 15249124 15604093 23975195 9121466 9171239 9751500 details
NCOA1NR2F6BioGRID, HPRD10713182 details
NCOA1PPARGC1ABioGRID, HPRD10558993 details
NCOA1CARM1BioGRID, HPRD10381882 16923966 18511550 details
NCOA1NKX2-1BioGRID, HPRD11076796 11713256 15449938 details
NCOA1PPARGBioGRID, HPRD10339548 10347167 10731636 10848596 11027271 11500849 11877444 15026545 15888456 17011503 17312272 17449869 17468099 17513608 17704298 19596656 20717101 22070604 23178929 23975195 30595551 30813326 9041124 9121466 9744270 details
NCOA1THRABioGRID, HPRD10379889 11117530 11435616 15140878 15249124 9804773 9849963 details
NCOA1EP300BioGRID, HPRD10973497 11113179 12208951 14722092 20368990 details
NCOA1RARGBioGRID, HPRD12665583 15604093 17363140 details
NCOA1NCOA6BioGRID10567404 12482968 21292004 details
NCOA1TP53BioGRID10551785 details
NCOA1COPS5BioGRID, HPRD10722692 details
NCOA1AHRBioGRID, HPRD12024042 15641800 details
NCOA1CXADRBioGRID15572376 details
NCOA1HNF4GBioGRID15604093 23975195 details
NCOA1NR6A1BioGRID23975195 details
NCOA1ARID1ABioGRID17363140 details
NCOA1BRCA1BioGRID16860316 details
NCOA1NR1H2BioGRID15604093 details
NCOA1RXRBBioGRID, HPRD15604093 7481822 details
NCOA1SRFBioGRID, HPRD9786846 details
NCOA1HNF1ABioGRID10777539 details
NCOA1NR3C2BioGRID10935545 15604093 details
NCOA1FOXO1BioGRID10973497 details
NCOA1ARNTBioGRID, HPRD10594042 12024042 details
NCOA1SMARCC1BioGRID15923603 details
NCOA1ANKRD11BioGRID15184363 details
NCOA1DDX5HPRD11250900 details
NCOA1NR2F1HPRD10652338 details
NCOA1NCOA1BioGRID, HPRD, IntAct10334992 10334993 23602807 9774463 details
NCOA1TDGIntAct16282588 details
NCOA1TNIKIntAct31413325 details
NCOA1NCOA2BioGRID11971985 18267973 9751728 9774463 details
NCOA1TRIM21BioGRID11971985 details
NCOA1STAT5ABioGRID12954634 details
NCOA1RBBP6BioGRID16051665 20184719 details
NCOA1UBE2L3BioGRID15367689 details
NCOA1TRIM24BioGRID9774463 details
NCOA1EZH2BioGRID17502350 details
NCOA1ETS2BioGRID15788656 details
NCOA1ETS1BioGRID15788656 details
NCOA1SF1BioGRID16002533 details
NCOA1WDHD1BioGRID16051665 details
NCOA1SYTL2BioGRID16051665 details
NCOA1HSPA2BioGRID16051665 details
NCOA1HSPA5BioGRID16051665 details
NCOA1KCTD3BioGRID16051665 details
NCOA1VCPBioGRID16051665 details
NCOA1ITCHBioGRID16051665 details
NCOA1TRIP11BioGRID16051665 details
NCOA1UBR5BioGRID16051665 details
NCOA1SMAD3BioGRID16423881 details
NCOA1NR4A2BioGRID21757690 details
NCOA1SMG7BioGRID29395067 details
NCOA1MAPK1HPRD10660621 details
NCOA1YWHAHHPRD11266503 details
NCOA1SUMO1HPRD12529333 details
NCOA1PRMT2HPRD12039952 details
NCOA1RABGGTBBioGRID, IntAct26186194 28514442 details
NCOA1TRPC4APBioGRID, IntAct28514442 details
NCOA1SLX1ABioGRID, IntAct28514442 details
NCOA1SLX1BIntAct28514442 details
NCOA1PLA2G10BioGRID, IntAct28514442 details
NCOA1FAM131BBioGRID, IntAct28514442 details
NCOA1BRME1BioGRID, IntAct28514442 details
NCOA1NBEAL2IntAct29187380 details
NCOA1ASCC1BioGRID25219498 details
NCOA1ZDHHC18BioGRID30658672 details
NCOA1ZDHHC23BioGRID30658672 details
NCOA1ABCB11IntAct25675114 details
NCOA1TNIP2BioGRID27609421 details
NCOA1VIRMABioGRID29507755 details