Entity Details

Primary name MARCO
Entity type gene
Source Source Link

Details

PrimaryID8685
RefseqGene
SymbolMARCO
Namemacrophage receptor with collagenous structure
Chromosome2
Location2q14.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-01
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsMARCO_HUMAN

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001664 G protein-coupled receptor binding
GO:0001934 positive regulation of protein phosphorylation
GO:0004888 transmembrane signaling receptor activity
GO:0005044 scavenger receptor activity
GO:0005581 collagen trimer
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006897 endocytosis
GO:0006898 receptor-mediated endocytosis
GO:0006911 phagocytosis, engulfment
GO:0007166 cell surface receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0030666 endocytic vesicle membrane
GO:0038024 cargo receptor activity
GO:0038187 pattern recognition receptor activity
GO:0043277 apoptotic cell clearance
GO:0045087 innate immune response
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0097242 amyloid-beta clearance

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
MARCOSCGB3A2BioGRID, HPRD12847263 details
MARCOSCGB3A1BioGRID, HPRD12847263 details
MARCODDX55BioGRID26344197 details