Entity Details

Primary name CDK5R1
Entity type gene
Source Source Link

Details

PrimaryID8851
RefseqGene
SymbolCDK5R1
Namecyclin dependent kinase 5 regulatory subunit 1
Chromosome17
Location17q11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-03-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCD5R1_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000226 microtubule cytoskeleton organization
GO:0001764 neuron migration
GO:0002020 protease binding
GO:0004672 protein kinase activity
GO:0005509 calcium ion binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007158 neuron cell-cell adhesion
GO:0007213 G protein-coupled acetylcholine receptor signaling pathway
GO:0007411 axon guidance
GO:0007413 axonal fasciculation
GO:0007420 brain development
GO:0009792 embryo development ending in birth or egg hatching
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016241 regulation of macroautophagy
GO:0016301 kinase activity
GO:0016533 protein kinase 5 complex
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019901 protein kinase binding
GO:0021549 cerebellum development
GO:0021722 superior olivary nucleus maturation
GO:0021766 hippocampus development
GO:0021819 layer formation in cerebral cortex
GO:0030182 neuron differentiation
GO:0030295 protein kinase activator activity
GO:0030424 axon
GO:0030425 dendrite
GO:0030426 growth cone
GO:0030517 negative regulation of axon extension
GO:0031116 positive regulation of microtubule polymerization
GO:0031175 neuron projection development
GO:0031594 neuromuscular junction
GO:0032956 regulation of actin cytoskeleton organization
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0035255 ionotropic glutamate receptor binding
GO:0042501 serine phosphorylation of STAT protein
GO:0043005 neuron projection
GO:0043014 alpha-tubulin binding
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0043204 perikaryon
GO:0043231 intracellular membrane-bounded organelle
GO:0043292 contractile fiber
GO:0043525 positive regulation of neuron apoptotic process
GO:0043539 protein serine/threonine kinase activator activity
GO:0045296 cadherin binding
GO:0045348 positive regulation of MHC class II biosynthetic process
GO:0045664 regulation of neuron differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046875 ephrin receptor binding
GO:0048013 ephrin receptor signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0048487 beta-tubulin binding
GO:0048511 rhythmic process
GO:0051015 actin filament binding
GO:0061001 regulation of dendritic spine morphogenesis
GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity
GO:0090314 positive regulation of protein targeting to membrane
GO:0098693 regulation of synaptic vesicle cycle
GO:0098793 presynapse
GO:1901796 regulation of signal transduction by p53 class mediator
GO:2000273 positive regulation of signaling receptor activity

Diseases

Show/Hide Table

Interactions

69 interactions

InteractorPartnerSourcesPublicationsLink
CDK5R1TSC22D4BioGRID, HPRD, IntAct16189514 details
CDK5R1CDK5BioGRID, DIP, HPRD, IntAct10604467 11389014 11583627 12223541 14521924 15689152 17036052 17591690 17762160 20133653 21220307 22654103 23602568 25331900 26186194 26264872 28514442 28637746 31319193 details
CDK5R1AATKBioGRID, IntAct14521924 details
CDK5R1MTUS2BioGRID, IntAct21516116 25416956 31515488 details
CDK5R1NOTCH2NLABioGRID, IntAct25416956 31515488 details
CDK5R1MYBPHLIntAct32814053 details
CDK5R1C11orf65IntAct32814053 details
CDK5R1RAB3CIntAct32814053 details
CDK5R1PRAM1IntAct32814053 details
CDK5R1THAP7IntAct32814053 details
CDK5R1CRELD2IntAct32814053 details
CDK5R1MYNNIntAct32814053 details
CDK5R1PIAS4IntAct32814053 details
CDK5R1CAMTA2IntAct32814053 details
CDK5R1TPX2IntAct32814053 details
CDK5R1NEK6IntAct32814053 details
CDK5R1SLC25A11IntAct32814053 details
CDK5R1MAGEA2BIntAct32814053 details
CDK5R1MAGEA2IntAct32814053 details
CDK5R1EPCAMIntAct32814053 details
CDK5R1KLRC1IntAct32814053 details
CDK5R1DNASE1L1IntAct32814053 details
CDK5R1SETBioGRID, HPRD11741927 details
CDK5R1AMPHBioGRID, HPRD11113134 details
CDK5R1CDK16BioGRID, HPRD12084709 details
CDK5R1CDK5RAP2BioGRID, HPRD10721722 10915792 11882646 details
CDK5R1CDK5RAP1BioGRID, HPRD10721722 10915792 11882646 details
CDK5R1CDK5RAP3BioGRID, HPRD10721722 10915792 11882646 details
CDK5R1CAMK2ABioGRID12223541 details
CDK5R1ACTN1BioGRID, HPRD12223541 details
CDK5R1CTNNB1BioGRID, HPRD10753743 11168528 details
CDK5R1HSP90AA1BioGRID20618441 details
CDK5R1NEDD4BioGRID19953087 details
CDK5R1ODF1BioGRID17762160 details
CDK5R1APPBioGRID21832049 details
CDK5R1SIAH1BioGRID25416956 details
CDK5R1BLOC1S6BioGRID25416956 details
CDK5R1KRT40BioGRID25416956 details
CDK5R1KRTAP10-3BioGRID25416956 details
CDK5R1GSK3BBioGRID25331900 details
CDK5R1SEPTIN5BioGRID18385322 details
CDK5R1LMTK2HPRD12832520 details
CDK5R1CHN1HPRD15013773 details
CDK5R1CDK2BioGRID, IntAct22654103 26186194 28514442 details
CDK5R1HDAC1BioGRID19081376 details
CDK5R1NESBioGRID, HPRD12832492 17036052 details
CDK5R1CDK3BioGRID22654103 details
CDK5R1CDK4BioGRID22654103 details
CDK5R1CDK6BioGRID22654103 details
CDK5R1CDK9BioGRID, HPRD12037672 22654103 details
CDK5R1DNMT1BioGRID26602018 details
CDK5R1PPP1R9BBioGRID28634551 details
CDK5R1PAK1HPRD11604394 details
CDK5R1TTBK1HPRD7556643 details
CDK5R1CAPN1HPRD10830966 details
CDK5R1CAPN2HPRD10830966 details
CDK5R1STXBP1HPRD9933594 details
CDK5R1CDK5R1HPRD11389014 details
CDK5R1MMABBioGRID, IntAct28514442 details
CDK5R1UBE2TBioGRID, IntAct26186194 28514442 details
CDK5R1MVB12ABioGRID, IntAct28514442 details
CDK5R1RSPRY1BioGRID, IntAct28514442 details
CDK5R1UBXN1BioGRID, IntAct28514442 details
CDK5R1HMGCS1BioGRID, IntAct26186194 28514442 details
CDK5R1TPM2BioGRID, IntAct26186194 28514442 details
CDK5R1PLPBPBioGRID, IntAct26186194 28514442 details
CDK5R1DENRBioGRID, IntAct26186194 28514442 details
CDK5R1TNIP2BioGRID27609421 details
CDK5R1VIRMABioGRID29507755 details