Entity Details

Primary name SPA12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IW75
EntryNameSPA12_HUMAN
FullNameSerpin A12
TaxID9606
Evidenceevidence at protein level
Length414
SequenceStatuscomplete
DateCreated2005-09-27
DateModified2021-06-02

Ontological Relatives

GenesSERPINA12

GO terms

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GOName
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0010951 negative regulation of endopeptidase activity
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0045721 negative regulation of gluconeogenesis
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0051055 negative regulation of lipid biosynthetic process
GO:0090181 regulation of cholesterol metabolic process
GO:0090207 regulation of triglyceride metabolic process

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000215 Serpin familyFamilyFamily
IPR023796 Serpin domainDomainDomain
IPR036186 Serpin superfamilyFamilyHomologous superfamily
IPR042178 Serpin superfamily, domain 1FamilyHomologous superfamily
IPR042185 Serpin superfamily, domain 2FamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SPA12_HUMAN3MG_HUMANBioGRID23537643 details