Entity Details

Primary name LEMD2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NC56
EntryNameLEMD2_HUMAN
FullNameLEM domain-containing protein 2
TaxID9606
Evidenceevidence at protein level
Length503
SequenceStatuscomplete
DateCreated2007-05-01
DateModified2021-06-02

Ontological Relatives

GenesLEMD2

GO terms

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GOName
GO:0005635 nuclear envelope
GO:0005637 nuclear inner membrane
GO:0005639 integral component of nuclear inner membrane
GO:0006998 nuclear envelope organization
GO:0007084 mitotic nuclear membrane reassembly
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0022008 neurogenesis
GO:0030514 negative regulation of BMP signaling pathway
GO:0031490 chromatin DNA binding
GO:0031965 nuclear membrane
GO:0035914 skeletal muscle cell differentiation
GO:0043409 negative regulation of MAPK cascade
GO:0051898 negative regulation of protein kinase B signaling
GO:0060914 heart formation
GO:0071168 protein localization to chromatin

Subcellular Location

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Subcellular Location
Nucleus inner membrane

Domains

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DomainNameCategoryType
IPR003887 LEM domainDomainDomain
IPR011015 LEM/LEM-like domain superfamilyFamilyHomologous superfamily
IPR018996 Man1/Src1, C-terminalDomainDomain
IPR034994 LEM domain-containing protein 2FamilyFamily
IPR041885 MAN1, winged-helix domainFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
LEMD2_HUMANLMNA_HUMANBioGRID, IntAct, UniProt16339967 29568061 details
LEMD2_HUMANOGT1_HUMANBioGRID32994395 details
LEMD2_HUMANSH3K1_HUMANBioGRID19531213 details