Entity Details

Primary name CCS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14618
EntryNameCCS_HUMAN
FullNameCopper chaperone for superoxide dismutase
TaxID9606
Evidenceevidence at protein level
Length274
SequenceStatuscomplete
DateCreated2002-01-31
DateModified2021-06-02

Ontological Relatives

GenesCCS

GO terms

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GOName
GO:0005507 copper ion binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006801 superoxide metabolic process
GO:0015680 protein maturation by copper ion transfer
GO:0019430 removal of superoxide radicals
GO:0034599 cellular response to oxidative stress
GO:0045296 cadherin binding
GO:0051353 positive regulation of oxidoreductase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001424 Superoxide dismutase, copper/zinc binding domainDomainDomain
IPR006121 Heavy metal-associated domain, HMADomainDomain
IPR018152 Superoxide dismutase, copper/zinc, binding siteSiteBinding site
IPR024134 Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperoneFamilyFamily
IPR036163 Heavy metal-associated domain superfamilyFamilyHomologous superfamily
IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule