Entity Details

Primary name KREM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96MU8
EntryNameKREM1_HUMAN
FullNameKremen protein 1
TaxID9606
Evidenceevidence at protein level
Length473
SequenceStatuscomplete
DateCreated2002-05-15
DateModified2021-06-02

Ontological Relatives

GenesKREMEN1

GO terms

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GOName
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0007154 cell communication
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016055 Wnt signaling pathway
GO:0030279 negative regulation of ossification
GO:0043025 neuronal cell body
GO:0048681 negative regulation of axon regeneration
GO:0060173 limb development
GO:0060828 regulation of canonical Wnt signaling pathway
GO:0090090 negative regulation of canonical Wnt signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000001 KringleDomainDomain
IPR000859 CUB domainDomainDomain
IPR002889 Carbohydrate-binding WSCDomainDomain
IPR013806 Kringle-like foldFamilyHomologous superfamily
IPR017076 KremenFamilyFamily
IPR018056 Kringle, conserved siteSiteConserved site
IPR035914 Spermadhesin, CUB domain superfamilyFamilyHomologous superfamily
IPR038178 Kringle superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
KREM1_HUMANPCNA_HUMANUniProt26030842 details
KREM1_HUMANDKK1_HUMANDIP, HPRD12050670 17804805 details