Entity Details

Primary name PG12A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BZM1
EntryNamePG12A_HUMAN
FullNameGroup XIIA secretory phospholipase A2
TaxID9606
Evidenceevidence at protein level
Length189
SequenceStatuscomplete
DateCreated2002-02-11
DateModified2021-06-02

Ontological Relatives

GenesPLA2G12A

GO terms

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GOName
GO:0004623 phospholipase A2 activity
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0006654 phosphatidic acid biosynthetic process
GO:0016042 lipid catabolic process
GO:0036148 phosphatidylglycerol acyl-chain remodeling
GO:0036149 phosphatidylinositol acyl-chain remodeling
GO:0036150 phosphatidylserine acyl-chain remodeling
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0036152 phosphatidylethanolamine acyl-chain remodeling
GO:0047498 calcium-dependent phospholipase A2 activity
GO:0050482 arachidonic acid secretion
GO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
GO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)

Subcellular Location

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Subcellular Location
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR010711 Group XII secretory phospholipase A2 precursorFamilyFamily
IPR033113 Phospholipase A2, histidine active siteSiteActive site
IPR036444 Phospholipase A2 domain superfamilyFamilyHomologous superfamily

Diseases

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