Entity Details

Primary name AL8A1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H2A2
EntryNameAL8A1_HUMAN
FullName2-aminomuconic semialdehyde dehydrogenase
TaxID9606
Evidenceevidence at protein level
Length487
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesALDH8A1

GO terms

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GOName
GO:0001758 retinal dehydrogenase activity
GO:0005829 cytosol
GO:0042573 retinoic acid metabolic process
GO:0042574 retinal metabolic process
GO:0042904 9-cis-retinoic acid biosynthetic process
GO:0047102 aminomuconate-semialdehyde dehydrogenase activity
GO:0070062 extracellular exosome
GO:0097053 L-kynurenine catabolic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR015590 Aldehyde dehydrogenase domainDomainDomain
IPR016160 Aldehyde dehydrogenase, cysteine active siteSiteConserved site
IPR016161 Aldehyde/histidinol dehydrogenaseFamilyHomologous superfamily
IPR016162 Aldehyde dehydrogenase, N-terminalFamilyHomologous superfamily
IPR016163 Aldehyde dehydrogenase, C-terminalFamilyHomologous superfamily
IPR029510 Aldehyde dehydrogenase, glutamic acid active siteSiteConserved site

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
AL8A1_HUMANA4_HUMANBioGRID21832049 details