Entity Details

Primary name GMPR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9P2T1
EntryNameGMPR2_HUMAN
FullNameGMP reductase 2
TaxID9606
Evidenceevidence at protein level
Length348
SequenceStatuscomplete
DateCreated2002-11-08
DateModified2021-06-02

Ontological Relatives

GenesGMPR2

GO terms

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GOName
GO:0003920 GMP reductase activity
GO:0005829 cytosol
GO:0006144 purine nucleobase metabolic process
GO:0043101 purine-containing compound salvage
GO:0046037 GMP metabolic process
GO:0046872 metal ion binding
GO:1902560 GMP reductase complex

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001093 IMP dehydrogenase/GMP reductaseDomainDomain
IPR005993 GMP reductaseFamilyFamily
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR015875 IMP dehydrogenase / GMP reductase, conserved siteSiteConserved site

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
GMPR2_HUMANERBB2_HUMANBioGRID, IntAct, MINT25640309 31980649 details
GMPR2_HUMANMEOX2_HUMANBioGRID, IntAct25416956 details
GMPR2_HUMANADRB2_HUMANBioGRID24561123 details