Entity Details

Primary name REV1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBZ9
EntryNameREV1_HUMAN
FullNameDNA repair protein REV1
TaxID9606
Evidenceevidence at protein level
Length1251
SequenceStatuscomplete
DateCreated2005-02-15
DateModified2021-06-02

Ontological Relatives

GenesREV1

GO terms

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GOName
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005654 nucleoplasm
GO:0006260 DNA replication
GO:0009411 response to UV
GO:0017125 deoxycytidyl transferase activity
GO:0019985 translesion synthesis
GO:0042276 error-prone translesion synthesis
GO:0046872 metal ion binding
GO:0070987 error-free translesion synthesis

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001126 UmuC domainDomainDomain
IPR001357 BRCT domainDomainDomain
IPR012112 DNA repair protein Rev1FamilyFamily
IPR017961 DNA polymerase, Y-family, little finger domainDomainDomain
IPR025527 HUWE1/Rev1, ubiquitin binding regionRepeatRepeat
IPR031991 DNA repair protein Rev1, C-terminalDomainDomain
IPR036420 BRCT domain superfamilyFamilyHomologous superfamily
IPR036775 DNA polymerase, Y-family, little finger domain superfamilyFamilyHomologous superfamily
IPR038401 Rev1, C-terminal domain superfamilyFamilyHomologous superfamily
IPR043128 Reverse transcriptase/Diguanylate cyclase domainFamilyHomologous superfamily
IPR043502 DNA/RNA polymerase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

25 interactions

InteractorPartnerSourcesPublicationsLink
REV1_HUMANFHL2_HUMANBioGRID, HPRD, MINT10906324 details
REV1_HUMANMD2L2_HUMANBioGRID, HPRD, MINT11485998 12529368 15189446 15380106 20164194 21690293 21926160 22303021 22828282 22859296 23287467 30111544 30154076 details
REV1_HUMANPOLH_HUMANBioGRID, HPRD, MINT15189446 15380106 16824193 19170759 21690293 22691049 22828282 details
REV1_HUMANFAP20_HUMANBioGRID, MINT22266823 26318859 details
REV1_HUMANPDIP2_HUMANBioGRID20554254 details
REV1_HUMANPCNA_HUMANBioGRID21690293 23761444 25614517 details
REV1_HUMANUBC_HUMANBioGRID21690293 31699778 details
REV1_HUMANPOLK_HUMANBioGRID, HPRD15189446 15380106 19170759 26903512 26982350 details
REV1_HUMANPOLI_HUMANBioGRID, HPRD15189446 19170759 30886224 details
REV1_HUMANREV3L_HUMANBioGRID, HPRD15189446 20164194 21926160 30111544 details
REV1_HUMANREV1_HUMANBioGRID19170759 details
REV1_HUMANDPOD3_HUMANBioGRID23254330 26982350 details
REV1_HUMANCLK1_HUMANBioGRID26167880 details
REV1_HUMANT22D2_HUMANBioGRID27337956 details
REV1_HUMANHS90A_HUMANBioGRID21690293 details
REV1_HUMANHS90B_HUMANBioGRID21690293 details
REV1_HUMANCDC27_HUMANBioGRID23287467 details
REV1_HUMANBRCA1_HUMANBioGRID23901102 details
REV1_HUMANMSH2_HUMANBioGRID24038355 details
REV1_HUMANTF65_HUMANBioGRID25331947 details
REV1_HUMANPIAS4_HUMANBioGRID25614517 details
REV1_HUMANP53_HUMANBioGRID25614517 details
REV1_HUMANFACD2_HUMANBioGRID26187992 details
REV1_HUMANFANCI_HUMANBioGRID26187992 details
REV1_HUMANDPOLL_HUMANHPRD14657033 details