Entity Details

Primary name GMDS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60547
EntryNameGMDS_HUMAN
FullNameGDP-mannose 4,6 dehydratase
TaxID9606
Evidenceevidence at protein level
Length372
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesGMDS

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007219 Notch signaling pathway
GO:0008446 GDP-mannose 4,6-dehydratase activity
GO:0019673 GDP-mannose metabolic process
GO:0042351 'de novo' GDP-L-fucose biosynthetic process
GO:0042802 identical protein binding
GO:0070062 extracellular exosome
GO:0070401 NADP+ binding

Subcellular Location

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Domains

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DomainNameCategoryType
IPR006368 GDP-mannose 4,6-dehydrataseFamilyFamily
IPR016040 NAD(P)-binding domainDomainDomain
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02547 Guanosine-5'-Diphosphate-RhamnoseDrugbanksmall molecule
DB04315 Guanosine-5'-DiphosphateDrugbanksmall molecule

Interactions

4 interactions