Entity Details

Primary name ST17B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94768
EntryNameST17B_HUMAN
FullNameSerine/threonine-protein kinase 17B
TaxID9606
Evidenceevidence at protein level
Length372
SequenceStatuscomplete
DateCreated2001-06-20
DateModified2021-06-02

Ontological Relatives

GenesSTK17B

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0015629 actin cytoskeleton
GO:0035556 intracellular signal transduction
GO:0043065 positive regulation of apoptotic process
GO:0046777 protein autophosphorylation
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000271 positive regulation of fibroblast apoptotic process

Subcellular Location

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Subcellular Location
Cell membrane
Endoplasmic reticulum-Golgi intermediate compartment
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR042763 Serine/threonine-protein kinase 17B, catalytic domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB04216 QuercetinDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule

Interactions

4 interactions