Entity Details

Primary name I18RA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95256
EntryNameI18RA_HUMAN
FullNameInterleukin-18 receptor accessory protein
TaxID9606
Evidenceevidence at protein level
Length599
SequenceStatuscomplete
DateCreated2005-09-27
DateModified2021-06-02

Ontological Relatives

GenesIL18RAP

GO terms

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GOName
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0008283 cell population proliferation
GO:0035655 interleukin-18-mediated signaling pathway
GO:0042008 interleukin-18 receptor activity
GO:0042119 neutrophil activation
GO:0045092 interleukin-18 receptor complex
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0050135 NAD(P)+ nucleosidase activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
GO:0070301 cellular response to hydrogen peroxide

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000157 Toll/interleukin-1 receptor homology (TIR) domainDomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015621 Interleukin-1 receptor familyFamilyFamily
IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR041416 IL-1Ra-like, immunoglobulin domainDomainDomain

Diseases

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