Entity Details

Primary name ALDOA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP04075
EntryNameALDOA_HUMAN
FullNameFructose-bisphosphate aldolase A
TaxID9606
Evidenceevidence at protein level
Length364
SequenceStatuscomplete
DateCreated1986-11-01
DateModified2021-06-02

Ontological Relatives

GenesALDOA

GO terms

Show/Hide Table
GOName
GO:0002576 platelet degranulation
GO:0003723 RNA binding
GO:0003779 actin binding
GO:0004332 fructose-bisphosphate aldolase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006000 fructose metabolic process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0006754 ATP biosynthetic process
GO:0006941 striated muscle contraction
GO:0007015 actin filament organization
GO:0007339 binding of sperm to zona pellucida
GO:0008092 cytoskeletal protein binding
GO:0008360 regulation of cell shape
GO:0015629 actin cytoskeleton
GO:0015631 tubulin binding
GO:0016020 membrane
GO:0030388 fructose 1,6-bisphosphate metabolic process
GO:0031093 platelet alpha granule lumen
GO:0031430 M band
GO:0031674 I band
GO:0034774 secretory granule lumen
GO:0042802 identical protein binding
GO:0043312 neutrophil degranulation
GO:0045296 cadherin binding
GO:0046716 muscle cell cellular homeostasis
GO:0051289 protein homotetramerization
GO:0061621 canonical glycolysis
GO:0061827 sperm head
GO:0070061 fructose binding
GO:0070062 extracellular exosome
GO:1904724 tertiary granule lumen
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000741 Fructose-bisphosphate aldolase, class-IFamilyFamily
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR029768 Fructose-bisphosphate aldolase class-I active siteSiteConserved site

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB02512 1,6-Fructose Diphosphate (Linear Form)Drugbanksmall molecule
DB04326 Dihydroxyacetone phosphateDrugbanksmall molecule
DB04733 1,6-DI-O-PHOSPHONO-D-MANNITOLDrugbanksmall molecule
DB08240 N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDEDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule

Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
ALDOA_HUMANXRN1_HUMANBioGRID, HPRD, IntAct15231747 details
ALDOA_HUMANPCNA_HUMANBioGRID, MINT20849852 details
ALDOA_HUMANMLH1_HUMANBioGRID, IntAct20706999 details
ALDOA_HUMANCAC1A_HUMANBioGRID, IntAct21078624 details
ALDOA_HUMANGALT6_HUMANBioGRID, IntAct21988832 details
ALDOA_HUMANBCAT2_HUMANBioGRID, IntAct21988832 details
ALDOA_HUMANALDOB_HUMANBioGRID, IntAct21988832 details
ALDOA_HUMANALDOA_HUMANBioGRID, HPRD, IntAct14669989 21988832 25416956 32296183 details
ALDOA_HUMANPIAS4_HUMANBioGRID, IntAct21988832 details
ALDOA_HUMANEGFR_HUMANBioGRID, IntAct20029029 31980649 details
ALDOA_HUMANENOA_HUMANBioGRID, IntAct23414517 26344197 details
ALDOA_HUMANENOB_HUMANBioGRID, IntAct23414517 details
ALDOA_HUMANAP2A_HUMANIntAct24835590 details
ALDOA_HUMANALDOC_HUMANBioGRID, IntAct22863883 22939629 25416956 25910212 26186194 26344197 26496610 28514442 31515488 31536960 details
ALDOA_HUMANIFNA4_HUMANBioGRID, IntAct25416956 details
ALDOA_HUMANTERF1_HUMANbhf-ucl, BioGRID21044950 details
ALDOA_HUMANHSPB2_HUMANbhf-ucl, BioGRID26465331 details
ALDOA_HUMANCRYAB_HUMANbhf-ucl26465331 details
ALDOA_HUMANHD_HUMANBioGRID, IntAct, UniProt25959826 32814053 details
ALDOA_HUMANZP4_HUMANIntAct23355646 details
ALDOA_HUMANERBB2_HUMANBioGRID, IntAct31980649 details
ALDOA_HUMANERBB3_HUMANBioGRID, IntAct31980649 details
ALDOA_HUMANERBB4_HUMANBioGRID, IntAct31980649 details
ALDOA_HUMANFANCA_HUMANBioGRID14499622 details
ALDOA_HUMANVATE1_HUMANBioGRID, HPRD11399750 details
ALDOA_HUMANPLD2_HUMANBioGRID, HPRD11876650 details
ALDOA_HUMANTRI63_HUMANBioGRID15967462 details
ALDOA_HUMANMYOC_HUMANBioGRID, HPRD16289162 details
ALDOA_HUMANADRB2_HUMANBioGRID24561123 details
ALDOA_HUMANHCD2_HUMANBioGRID22496890 26344197 details
ALDOA_HUMANSRPK2_HUMANBioGRID26167880 details
ALDOA_HUMANCYH2_HUMANBioGRID21307348 details
ALDOA_HUMANS22A1_HUMANBioGRID31318583 details
ALDOA_HUMANOGT1_HUMANBioGRID32994395 details
ALDOA_HUMAN1433Z_HUMANMINT15161933 details
ALDOA_HUMANSHAN3_HUMANMINT21653829 details
ALDOA_HUMANPSMD4_HUMANBioGRID12601813 details
ALDOA_HUMANHDAC5_HUMANBioGRID21081666 details
ALDOA_HUMANISG15_HUMANBioGRID16009940 33024031 details
ALDOA_HUMANAKT1_HUMANBioGRID16027165 details
ALDOA_HUMANHS90A_HUMANBioGRID16263121 details
ALDOA_HUMANMT21D_HUMANBioGRID23349634 details
ALDOA_HUMANSUMO4_HUMANBioGRID, HPRD16236267 26344197 details
ALDOA_HUMANFLCN_HUMANBioGRID28656962 details
ALDOA_HUMANATG5_HUMANBioGRID33024031 details
ALDOA_HUMANGPDM_HUMANHPRD2065091 6406231 details
ALDOA_HUMANTGM2_HUMANHPRD1353685 details
ALDOA_HUMANTBB2A_HUMANHPRD8103323 details
ALDOA_HUMANDYL1_HUMANHPRD14760703 details