Entity Details

Primary name ARLY_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP04424
EntryNameARLY_HUMAN
FullNameArgininosuccinate lyase
TaxID9606
Evidenceevidence at protein level
Length464
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesASL

GO terms

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GOName
GO:0000050 urea cycle
GO:0004056 argininosuccinate lyase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0042450 arginine biosynthetic process via ornithine
GO:0042802 identical protein binding
GO:0070062 extracellular exosome

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000362 Fumarate lyase familyFamilyFamily
IPR008948 L-Aspartase-likeFamilyHomologous superfamily
IPR009049 Argininosuccinate lyaseFamilyFamily
IPR020557 Fumarate lyase, conserved siteSiteConserved site
IPR022761 Fumarate lyase, N-terminalDomainDomain
IPR024083 Fumarase/histidase, N-terminalFamilyHomologous superfamily
IPR029419 Argininosuccinate lyase, C-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00125 ArginineDrugbanksmall molecule
DB02267 ArgininosuccinateDrugbanksmall molecule
DB03814 2-(N-morpholino)ethanesulfonic acidDrugbanksmall molecule