Entity Details

Primary name PTN4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP29074
EntryNamePTN4_HUMAN
FullNameTyrosine-protein phosphatase non-receptor type 4
TaxID9606
Evidenceevidence at protein level
Length926
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesPTPN4

GO terms

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GOName
GO:0004725 protein tyrosine phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0006470 protein dephosphorylation
GO:0008092 cytoskeletal protein binding
GO:0009898 cytoplasmic side of plasma membrane
GO:0071345 cellular response to cytokine stimulus

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000299 FERM domainDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR012151 Protein-tyrosine phosphatase, non-receptor type-3, -4FamilyFamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR014847 FERM adjacent (FA)DomainDomain
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR018979 FERM, N-terminalDomainDomain
IPR018980 FERM, C-terminal PH-like domainDomainDomain
IPR019747 FERM conserved siteSiteConserved site
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR041783 PTPN3/4, FERM domain C-lobeDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00630 Alendronic acidDrugbanksmall molecule