Entity Details

Primary name VPS41_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49754
EntryNameVPS41_HUMAN
FullNameVacuolar protein sorting-associated protein 41 homolog
TaxID9606
Evidenceevidence at protein level
Length854
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesVPS41

GO terms

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GOName
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005794 Golgi apparatus
GO:0005798 Golgi-associated vesicle
GO:0005829 cytosol
GO:0006623 protein targeting to vacuole
GO:0008017 microtubule binding
GO:0008333 endosome to lysosome transport
GO:0009267 cellular response to starvation
GO:0010008 endosome membrane
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0016236 macroautophagy
GO:0030123 AP-3 adaptor complex
GO:0030136 clathrin-coated vesicle
GO:0030897 HOPS complex
GO:0031902 late endosome membrane
GO:0034058 endosomal vesicle fusion
GO:0042802 identical protein binding
GO:0043621 protein self-association
GO:0045055 regulated exocytosis
GO:0046872 metal ion binding
GO:0048193 Golgi vesicle transport
GO:1902501 lysosomal HOPS complex
GO:1902774 late endosome to lysosome transport

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle
Early endosome
Endosome membrane
Golgi apparatus
Late endosome
Lysosome

Domains

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DomainNameCategoryType
IPR000547 Clathrin, heavy chain/VPS, 7-fold repeatRepeatRepeat
IPR001841 Zinc finger, RING-typeDomainDomain
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016902 Vacuolar protein sorting-associated protein 41FamilyFamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

25 interactions

InteractorPartnerSourcesPublicationsLink
VPS41_HUMANZ512B_HUMANBioGRID, MINT15231748 details
VPS41_HUMANUBE2U_HUMANBioGRID, IntAct19690564 details
VPS41_HUMANMON1B_HUMANBioGRID, IntAct20434987 details
VPS41_HUMANVPS18_HUMANBioGRID, IntAct22939629 23901104 25783203 26186194 26463206 26496610 28514442 28931724 33422265 details
VPS41_HUMANRILP_HUMANBioGRID, UniProt25445562 details
VPS41_HUMANVPS41_HUMANUniProt24210660 details
VPS41_HUMANA4_HUMANBioGRID21832049 details
VPS41_HUMANRAB7A_HUMANBioGRID25445562 details
VPS41_HUMANARL8B_HUMANBioGRID25908847 details
VPS41_HUMANSPE39_HUMANBioGRID, IntAct19109425 details
VPS41_HUMANHS90B_HUMANIntAct22939624 details
VPS41_HUMANVPS16_HUMANBioGRID, IntAct22939629 26186194 26463206 26496610 28514442 details
VPS41_HUMANVP33B_HUMANBioGRID, UniProt19109425 23918659 details
VPS41_HUMANSTX17_HUMANBioGRID, IntAct, UniProt24554770 33422265 details
VPS41_HUMANVPS11_HUMANBioGRID, IntAct26186194 26463206 28514442 28931724 33422265 details
VPS41_HUMANVP33A_HUMANBioGRID, IntAct22939629 26186194 26463206 28514442 28931724 details
VPS41_HUMANH2B2C_HUMANIntAct30021884 details
VPS41_HUMANVPS39_HUMANIntAct33422265 details
VPS41_HUMANHOOK1_HUMANBioGRID, HPRD18799622 details
VPS41_HUMANHOOK2_HUMANBioGRID, HPRD18799622 details
VPS41_HUMANHOOK3_HUMANBioGRID, HPRD18799622 details
VPS41_HUMANAKTIP_HUMANBioGRID, HPRD18799622 details
VPS41_HUMANHS90A_HUMANBioGRID22939624 details
VPS41_HUMANAP3D1_HUMANBioGRID, HPRD10559961 21411634 details
VPS41_HUMANCLCB_HUMANBioGRID21411634 details