Entity Details

Primary name PGTB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP53609
EntryNamePGTB1_HUMAN
FullNameGeranylgeranyl transferase type-1 subunit beta
TaxID9606
Evidenceevidence at protein level
Length377
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesPGGT1B

GO terms

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GOName
GO:0004661 protein geranylgeranyltransferase activity
GO:0004662 CAAX-protein geranylgeranyltransferase activity
GO:0005953 CAAX-protein geranylgeranyltransferase complex
GO:0008270 zinc ion binding
GO:0008284 positive regulation of cell population proliferation
GO:0018342 protein prenylation
GO:0018344 protein geranylgeranylation
GO:0034097 response to cytokine
GO:0036094 small molecule binding
GO:0042277 peptide binding
GO:0045787 positive regulation of cell cycle
GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001330 PFTB repeatRepeatRepeat
IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroidFamilyHomologous superfamily
IPR041960 Geranylgeranyl transferase type-1 subunit betaFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB07227 L-778123Drugbanksmall molecule
DB07841 Geranylgeranyl diphosphateDrugbanksmall molecule
DB08180 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATEDrugbanksmall molecule