Entity Details

Primary name STAT4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14765
EntryNameSTAT4_HUMAN
FullNameSignal transducer and activator of transcription 4
TaxID9606
Evidenceevidence at protein level
Length748
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesSTAT4

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006952 defense response
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0019221 cytokine-mediated signaling pathway
GO:0035722 interleukin-12-mediated signaling pathway
GO:0038114 interleukin-21-mediated signaling pathway
GO:0038155 interleukin-23-mediated signaling pathway
GO:0042127 regulation of cell population proliferation
GO:0042802 identical protein binding
GO:0043434 response to peptide hormone
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0070757 interleukin-35-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001217 Transcription factor STATFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR012345 STAT transcription factor, DNA-binding, N-terminalFamilyHomologous superfamily
IPR013799 STAT transcription factor, protein interactionDomainDomain
IPR013800 STAT transcription factor, all-alpha domainDomainDomain
IPR013801 STAT transcription factor, DNA-bindingDomainDomain
IPR015988 STAT transcription factor, coiled coilFamilyHomologous superfamily
IPR029839 Signal transducer and activator of transcription 4FamilyFamily
IPR035856 STAT4, SH2 domainDomainDomain
IPR036535 STAT transcription factor, N-terminal domain superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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