Entity Details

Primary name PDP1
Entity type gene
Source Source Link

Details

PrimaryID54704
RefseqGeneNG_012233
SymbolPDP1
Namepyruvate dehydrogenase phosphatase catalytic subunit 1
Chromosome8
Location8q22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-03
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsPDP1_HUMAN

GO terms

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GOName
GO:0004722 protein serine/threonine phosphatase activity
GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006470 protein dephosphorylation
GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0035970 peptidyl-threonine dephosphorylation
GO:0046872 metal ion binding
GO:1904184 positive regulation of pyruvate dehydrogenase activity

Diseases

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Interactions

69 interactions

InteractorPartnerSourcesPublicationsLink
PDP1PDHA1BioGRID, HPRD, MINT24486017 34079125 7782287 details
PDP1CBFA2T2BioGRID, IntAct25416956 details
PDP1INCA1BioGRID, IntAct32296183 details
PDP1KRTAP6-2BioGRID, IntAct32296183 details
PDP1ACAT1BioGRID24486017 details
PDP1SIRT3BioGRID24486017 details
PDP1FGFR1BioGRID24486017 details
PDP1EGFRBioGRID24486017 details
PDP1MEOX2BioGRID32296183 details
PDP1OGTBioGRID32994395 details
PDP1DISC1IntAct31413325 details
PDP1PRKCDBioGRID, HPRD11577086 details
PDP1SIRT4IntAct25525879 details
PDP1PCGF2BioGRID, IntAct28514442 details
PDP1SAMD4ABioGRID, IntAct28514442 details
PDP1TRMT1BioGRID, IntAct28514442 details
PDP1WDR44BioGRID, IntAct28514442 details
PDP1BMP4BioGRID, IntAct28514442 details
PDP1MRPL37BioGRID, IntAct26186194 28514442 details
PDP1SDHABioGRID, IntAct28514442 details
PDP1SPRED2BioGRID, IntAct28514442 details
PDP1PLEKHG5BioGRID, IntAct28514442 details
PDP1SAMD4BBioGRID, IntAct28514442 details
PDP1MTMR14BioGRID, IntAct28514442 details
PDP1SNUPNBioGRID, IntAct26186194 28514442 details
PDP1PDK1BioGRID, IntAct29568061 details
PDP1PAK1BioGRID, IntAct31980649 details
PDP1RHOABioGRID, IntAct31980649 details
PDP1CLEC18ABioGRID26186194 details
PDP1CORO1CBioGRID27880917 details
PDP1PDPRBioGRID27880917 details
PDP1PMPCABioGRID27880917 details
PDP1PMPCBBioGRID27880917 details
PDP1SPTAN1BioGRID27880917 details
PDP1SPTBN1BioGRID27880917 details
PDP1HIF1ABioGRID27320910 details
PDP1AK2BioGRID31536960 details
PDP1PRDX1BioGRID31536960 details
PDP1ACO2BioGRID31536960 details
PDP1ARCN1BioGRID31536960 details
PDP1C1orf198BioGRID31536960 details
PDP1GATD3BioGRID31536960 details
PDP1CLIC1BioGRID31536960 details
PDP1CMPK1BioGRID31536960 details
PDP1DDAH1BioGRID31536960 details
PDP1DDAH2BioGRID31536960 details
PDP1ENO1BioGRID31536960 details
PDP1FEN1BioGRID31536960 details
PDP1GCSHBioGRID31536960 details
PDP1HDHD3BioGRID31536960 details
PDP1HINT1BioGRID31536960 details
PDP1HINT2BioGRID31536960 details
PDP1IDH2BioGRID31536960 details
PDP1LACTB2BioGRID31536960 details
PDP1MPSTBioGRID31536960 details
PDP1NDUFAB1BioGRID31536960 details
PDP1NOS2BioGRID31536960 details
PDP1PARK7BioGRID31536960 details
PDP1CLIC4BioGRID31536960 details
PDP1GRHPRBioGRID31536960 details
PDP1NENFBioGRID31536960 details
PDP1PGLSBioGRID31536960 details
PDP1PPA2BioGRID31536960 details
PDP1PRDX6BioGRID31536960 details
PDP1RAB11FIP5BioGRID31536960 details
PDP1SOD1BioGRID31536960 details
PDP1UCHL1BioGRID31536960 details
PDP1AARS2BioGRID34079125 details
PDP1CSBioGRID34079125 details