Entity Details

Primary name PLEKHF1
Entity type gene
Source Source Link

Details

PrimaryID79156
RefseqGene
SymbolPLEKHF1
Namepleckstrin homology and FYVE domain containing 1
Chromosome19
Location19q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-07
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPKHF1_HUMAN

GO terms

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GOName
GO:0005634 nucleus
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0006915 apoptotic process
GO:0007032 endosome organization
GO:0010008 endosome membrane
GO:0010314 phosphatidylinositol-5-phosphate binding
GO:0010508 positive regulation of autophagy
GO:0016050 vesicle organization
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0035091 phosphatidylinositol binding
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0072659 protein localization to plasma membrane
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
PLEKHF1TNNT1BioGRID, HPRD, IntAct16189514 details
PLEKHF1KIFBPBioGRID, HPRD, IntAct16189514 details
PLEKHF1L3MBTL3BioGRID, IntAct25416956 32296183 details
PLEKHF1CAVIN2BioGRID, IntAct32296183 details
PLEKHF1CHIC2BioGRID, IntAct32296183 details
PLEKHF1NPM2BioGRID, IntAct32296183 details
PLEKHF1TNFAIP8BioGRID, IntAct32296183 details
PLEKHF1NHLRC2BioGRID30397336 details