Entity Details

Primary name OBSCN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5VST9
EntryNameOBSCN_HUMAN
FullNameObscurin
TaxID9606
Evidenceevidence at protein level
Length7968
SequenceStatuscomplete
DateCreated2006-05-16
DateModified2021-06-02

Ontological Relatives

GenesOBSCN

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007275 multicellular organism development
GO:0008307 structural constituent of muscle
GO:0010314 phosphatidylinositol-5-phosphate binding
GO:0016604 nuclear body
GO:0030016 myofibril
GO:0030018 Z disc
GO:0030506 ankyrin binding
GO:0031430 M band
GO:0031432 titin binding
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0036309 protein localization to M-band
GO:0042383 sarcolemma
GO:0043065 positive regulation of apoptotic process
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
GO:0045214 sarcomere organization
GO:0046872 metal ion binding
GO:0050839 cell adhesion molecule binding
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0098609 cell-cell adhesion
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR000219 Dbl homology (DH) domainDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR013098 Immunoglobulin I-setDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020682 ObscurinFamilyFamily
IPR035526 Obscurin, SH3 domainDomainDomain
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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