Entity Details

Primary name AMTN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6UX39
EntryNameAMTN_HUMAN
FullNameAmelotin
TaxID9606
Evidenceevidence at protein level
Length209
SequenceStatuscomplete
DateCreated2004-11-23
DateModified2021-06-02

Ontological Relatives

GenesAMTN

GO terms

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GOName
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005788 endoplasmic reticulum lumen
GO:0005911 cell-cell junction
GO:0007155 cell adhesion
GO:0031012 extracellular matrix
GO:0031214 biomineral tissue development
GO:0042475 odontogenesis of dentin-containing tooth
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0070169 positive regulation of biomineral tissue development
GO:0070175 positive regulation of enamel mineralization

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR031501 AmelotinFamilyFamily

Diseases

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Disease IDSourceNameDescription
617607 OMIMAmelogenesis imperfecta 3B (AI3B)An autosomal dominant form of amelogenesis imperfecta, a defect of enamel formation. AI3B is characterized by hypomineralized enamel that has reduced tickness and exhibits structural defects. The disease is caused by variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
AMTN_HUMANFA20C_HUMANIntAct25789606 details
AMTN_HUMANBAG6_HUMANBioGRID, IntAct32296183 details