Entity Details

Primary name CHD5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TDI0
EntryNameCHD5_HUMAN
FullNameChromodomain-helicase-DNA-binding protein 5
TaxID9606
Evidenceevidence at protein level
Length1954
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesCHD5

GO terms

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GOName
GO:0000792 heterochromatin
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008285 negative regulation of cell population proliferation
GO:0016020 membrane
GO:0016581 NuRD complex
GO:0016607 nuclear speck
GO:0016787 hydrolase activity
GO:0021895 cerebral cortex neuron differentiation
GO:0035093 spermatogenesis, exchange of chromosomal proteins
GO:0043967 histone H4 acetylation
GO:0046872 metal ion binding
GO:0061628 H3K27me3 modified histone binding
GO:0070615 nucleosome-dependent ATPase activity
GO:0098532 histone H3-K27 trimethylation
GO:1901798 positive regulation of signal transduction by p53 class mediator

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000330 SNF2, N-terminalDomainDomain
IPR000953 Chromo/chromo shadow domainDomainDomain
IPR001650 Helicase, C-terminalDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved siteSiteConserved site
IPR009462 Domain of unknown function DUF1086DomainDomain
IPR009463 Domain of unknown function DUF1087DomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR012957 CHD, C-terminal 2DomainDomain
IPR012958 CHD, N-terminalDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR016197 Chromo-like domain superfamilyFamilyHomologous superfamily
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR023780 Chromo domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR028727 Chromodomain-helicase-DNA-binding protein 5FamilyFamily
IPR038718 SNF2-like, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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