Entity Details

Primary name NDOR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UHB4
EntryNameNDOR1_HUMAN
FullNameNADPH-dependent diflavin oxidoreductase 1
TaxID9606
Evidenceevidence at protein level
Length597
SequenceStatuscomplete
DateCreated2008-02-26
DateModified2021-06-02

Ontological Relatives

GenesNDOR1

GO terms

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GOName
GO:0003958 NADPH-hemoprotein reductase activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0008219 cell death
GO:0008753 NADPH dehydrogenase (quinone) activity
GO:0010181 FMN binding
GO:0016226 iron-sulfur cluster assembly
GO:0016491 oxidoreductase activity
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0022900 electron transport chain
GO:0036245 cellular response to menadione
GO:0045111 intermediate filament cytoskeleton
GO:0048471 perinuclear region of cytoplasm
GO:0050660 flavin adenine dinucleotide binding
GO:0050661 NADP binding
GO:0070402 NADPH binding
GO:0071949 FAD binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001094 Flavodoxin-likeDomainDomain
IPR001433 Oxidoreductase FAD/NAD(P)-bindingDomainDomain
IPR001709 Flavoprotein pyridine nucleotide cytochrome reductaseDomainDomain
IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-bindingDomainDomain
IPR008254 Flavodoxin/nitric oxide synthaseDomainDomain
IPR017927 FAD-binding domain, ferredoxin reductase-typeDomainDomain
IPR017938 Riboflavin synthase-like beta-barrelFamilyHomologous superfamily
IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamilyFamilyHomologous superfamily
IPR028879 NADPH-dependent diflavin oxidoreductase 1FamilyFamily
IPR029039 Flavoprotein-like superfamilyFamilyHomologous superfamily
IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domainFamilyHomologous superfamily

Diseases

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Interactions

31 interactions

InteractorPartnerSourcesPublicationsLink
NDOR1_HUMANCPIN1_HUMANBioGRID, IntAct25416956 26186194 28514442 31515488 32296183 details
NDOR1_HUMANITF2_HUMANBioGRID, IntAct25416956 31515488 32296183 details
NDOR1_HUMANMTUS2_HUMANBioGRID, IntAct25416956 31515488 32296183 details
NDOR1_HUMANEFHC2_HUMANBioGRID, IntAct25416956 details
NDOR1_HUMANTCHP_HUMANBioGRID, IntAct25416956 31515488 32296183 details
NDOR1_HUMANUBQL1_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANUBQL2_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANRBTN2_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANPSB6_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANAP4AT_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANZN774_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANZN620_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANZBT42_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANLMO3_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANK0408_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANCATAC_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANDRC4_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANTLE5_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANNAB2_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANHXB2_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANGPS2_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANMEOX1_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANLNX1_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANNLK_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANZC21C_HUMANBioGRID, IntAct32296183 details
NDOR1_HUMANCCD33_HUMANBioGRID, IntAct25416956 31515488 details
NDOR1_HUMANCYC_HUMANBioGRID, HPRD10625700 details
NDOR1_HUMANCG057_HUMANBioGRID32296183 details
NDOR1_HUMANENOX2_HUMANBioGRID32296183 details
NDOR1_HUMANDLG4_HUMANHPRD7569905 details
NDOR1_HUMANNDOR1_HUMANBioGRID20802492 details