Entity Details

Primary name TRHDE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UKU6
EntryNameTRHDE_HUMAN
FullNameThyrotropin-releasing hormone-degrading ectoenzyme
TaxID9606
Evidenceevidence at transcript level
Length1024
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesTRHDE

GO terms

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GOName
GO:0004177 aminopeptidase activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006508 proteolysis
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008217 regulation of blood pressure
GO:0008270 zinc ion binding
GO:0042277 peptide binding
GO:0043171 peptide catabolic process
GO:0070006 metalloaminopeptidase activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolaseFamilyFamily
IPR014782 Peptidase M1, membrane alanine aminopeptidaseDomainDomain
IPR015570 Pyroglutamyl-peptidase IIFamilyFamily
IPR024571 ERAP1-like C-terminal domainDomainDomain
IPR034016 Aminopeptidase N-typeFamilyFamily
IPR042097 Aminopeptidase N-like , N-terminalFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TRHDE_HUMANREG3A_HUMANHPRD10662590 details
TRHDE_HUMANSCHI1_HUMANIntAct20195357 details