Entity Details

Primary name SYFM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95363
EntryNameSYFM_HUMAN
FullNamePhenylalanine--tRNA ligase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length451
SequenceStatuscomplete
DateCreated2004-11-23
DateModified2021-06-02

Ontological Relatives

GenesFARS2

GO terms

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GOName
GO:0000049 tRNA binding
GO:0004826 phenylalanine-tRNA ligase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006418 tRNA aminoacylation for protein translation
GO:0006432 phenylalanyl-tRNA aminoacylation
GO:0008033 tRNA processing

Subcellular Location

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Subcellular Location
Mitochondrion
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR002319 Phenylalanyl-tRNA synthetaseDomainDomain
IPR004530 Phenylalanyl-tRNA synthetase, class IIc, mitochondrialFamilyFamily
IPR005121 Ferrodoxin-fold anticodon-binding domainDomainDomain
IPR006195 Aminoacyl-tRNA synthetase, class IIDomainDomain
IPR036690 Ferrodoxin-fold anticodon-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00120 PhenylalanineDrugbanksmall molecule

Interactions

73 interactions

InteractorPartnerSourcesPublicationsLink
SYFM_HUMANSTX11_HUMANBioGRID, IntAct25416956 details
SYFM_HUMANTRI27_HUMANBioGRID, IntAct25416956 details
SYFM_HUMANTAD2A_HUMANBioGRID, IntAct25416956 details
SYFM_HUMANRCBT2_HUMANBioGRID, IntAct25416956 32296183 details
SYFM_HUMANKR109_HUMANBioGRID, IntAct25416956 32296183 details
SYFM_HUMANCACO2_HUMANBioGRID, IntAct25416956 31515488 32296183 details
SYFM_HUMANKR105_HUMANIntAct25416956 details
SYFM_HUMANKR107_HUMANBioGRID, IntAct25416956 32296183 details
SYFM_HUMANMKRN3_HUMANBioGRID, IntAct25416956 details
SYFM_HUMANK1C40_HUMANBioGRID, IntAct25416956 32296183 details
SYFM_HUMANATRAP_HUMANBioGRID, IntAct25416956 32296183 details
SYFM_HUMANK1H1_HUMANBioGRID, IntAct25416956 details
SYFM_HUMANTFCP2_HUMANBioGRID, IntAct25416956 details
SYFM_HUMANATL4_HUMANBioGRID, IntAct25416956 details
SYFM_HUMANCKLF5_HUMANBioGRID, IntAct25416956 32296183 details
SYFM_HUMANTRIM1_HUMANBioGRID, IntAct25416956 32296183 details
SYFM_HUMANCBY2_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANZN526_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANHMBX1_HUMANBioGRID, IntAct25416956 details
SYFM_HUMANDP13A_HUMANBioGRID, IntAct25416956 31515488 32296183 details
SYFM_HUMANDG2L6_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANDPH2_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANSPY1_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANNT2NA_HUMANBioGRID, IntAct25416956 details
SYFM_HUMANZRAN1_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANIKZF3_HUMANBioGRID, IntAct25416956 32296183 details
SYFM_HUMANTPM2_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANTRIP6_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANPP16B_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANTRI54_HUMANBioGRID, IntAct25416956 details
SYFM_HUMANBAG4_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANISY1_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANCRTP1_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANCC152_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANKR108_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANMDFI_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANBACH2_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANDVL3_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANKRA11_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANRAB43_HUMANIntAct32296183 details
SYFM_HUMANFHL5_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANSYPH_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANIKBD_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANMESD_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANBANP_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANAP1B1_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANZN655_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANZN438_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANFSD2_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANMORN3_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANRIM3A_HUMANIntAct32296183 details
SYFM_HUMANKCNF1_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANKRA33_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANTRAF2_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANKRT34_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANAJUBA_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANMA1C1_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANCDCA4_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANGRB10_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANHIG1C_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANBEX5_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANPCSK5_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANAP4AT_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANFKBP7_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANKCD17_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANK1C13_HUMANBioGRID25416956 details
SYFM_HUMANYIF1A_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANHOMEZ_HUMANBioGRID32296183 details
SYFM_HUMANMTUS2_HUMANIntAct30886144 details
SYFM_HUMANZN500_HUMANBioGRID, IntAct32296183 details
SYFM_HUMANKR103_HUMANBioGRID25416956 details
SYFM_HUMANNT2NC_HUMANBioGRID25416956 details
SYFM_HUMANRIM3C_HUMANBioGRID32296183 details