Entity Details

Primary name CNOT4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95628
EntryNameCNOT4_HUMAN
FullNameCCR4-NOT transcription complex subunit 4
TaxID9606
Evidenceevidence at protein level
Length575
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesCNOT4

GO terms

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GOName
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
GO:0003723 RNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0016567 protein ubiquitination
GO:0030014 CCR4-NOT complex
GO:0045652 regulation of megakaryocyte differentiation
GO:0046872 metal ion binding
GO:0051865 protein autoubiquitination

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR000571 Zinc finger, CCCH-typeDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR003954 RNA recognition motif domain, eukaryoteDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR034261 CNOT4, RNA recognition motifDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily
IPR039515 NOT4, modified RING finger, HC subclass (C4C4-type)DomainDomain
IPR039780 CCR4-NOT transcription complex subunit 4FamilyFamily

Diseases

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Interactions

28 interactions

InteractorPartnerSourcesPublicationsLink
CNOT4_HUMANUB2D2_HUMANBioGRID, HPRD, IntAct11823428 15001359 15062086 19690564 26575292 details
CNOT4_HUMANUB2D3_HUMANBioGRID, IntAct19690564 details
CNOT4_HUMANUB2D4_HUMANBioGRID, IntAct19690564 details
CNOT4_HUMANUB2E3_HUMANBioGRID, HPRD, IntAct11823428 15001359 19690564 details
CNOT4_HUMANUBE2N_HUMANBioGRID, IntAct19690564 details
CNOT4_HUMANUBE2W_HUMANBioGRID, IntAct19690564 details
CNOT4_HUMANEP300_HUMANBioGRID, IntAct21988832 details
CNOT4_HUMANCNOT1_HUMANBioGRID, HPRD, UniProt10637334 11823428 29802328 30692204 details
CNOT4_HUMANI36RA_HUMANBioGRID, IntAct32296183 details
CNOT4_HUMANKDM5C_HUMANBioGRID19346402 details
CNOT4_HUMANUB2E1_HUMANBioGRID, HPRD11823428 15001359 details
CNOT4_HUMANCNOT4_HUMANBioGRID11823428 15001359 details
CNOT4_HUMANUB2D1_HUMANBioGRID19346402 details
CNOT4_HUMANRBM15_HUMANBioGRID26575292 details
CNOT4_HUMANCNOT2_HUMANBioGRID29395067 30692204 details
CNOT4_HUMANCNOT3_HUMANBioGRID30692204 details
CNOT4_HUMANCNOT8_HUMANBioGRID, HPRD10637334 30692204 details
CNOT4_HUMANCNOT9_HUMANBioGRID29395067 30692204 details
CNOT4_HUMANUBE2B_HUMANHPRD15001359 details
CNOT4_HUMANMEX3B_HUMANBioGRID29395067 details
CNOT4_HUMANYTHD2_HUMANBioGRID29395067 details
CNOT4_HUMANYTHD3_HUMANBioGRID29395067 details
CNOT4_HUMANTTP_HUMANBioGRID29395067 details
CNOT4_HUMANTNR6B_HUMANBioGRID29395067 details
CNOT4_HUMANUBP2L_HUMANBioGRID29395067 details
CNOT4_HUMAN4ET_HUMANBioGRID29395067 details
CNOT4_HUMANTNR6A_HUMANBioGRID29395067 details
CNOT4_HUMANZ3H7A_HUMANBioGRID29395067 details