Entity Details

Primary name CFAB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP00751
EntryNameCFAB_HUMAN
FullNameComplement factor B
TaxID9606
Evidenceevidence at protein level
Length764
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesCFB

GO terms

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GOName
GO:0001848 complement binding
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0006956 complement activation
GO:0006957 complement activation, alternative pathway
GO:0030449 regulation of complement activation
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000436 Sushi/SCR/CCP domainDomainDomain
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR002035 von Willebrand factor, type ADomainDomain
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR011360 Complement B/C2FamilyFamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR028341 Complement factor BFamilyFamily
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR035976 Sushi/SCR/CCP superfamilyFamilyHomologous superfamily
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB02459 4-guanidinobenzoic acidDrugbanksmall molecule
DB04491 Diisopropylphosphono GroupDrugbanksmall molecule
DB06503 MLN2222Drugbankbiotech
DB14487 Zinc acetateDrugbanksmall molecule