Entity Details

Primary name ITB5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP18084
EntryNameITB5_HUMAN
FullNameIntegrin beta-5
TaxID9606
Evidenceevidence at protein level
Length799
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesITGB5

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005178 integrin binding
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006936 muscle contraction
GO:0007160 cell-matrix adhesion
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0009986 cell surface
GO:0016477 cell migration
GO:0030198 extracellular matrix organization
GO:0033627 cell adhesion mediated by integrin
GO:0034684 integrin alphav-beta5 complex
GO:0035987 endodermal cell differentiation
GO:0038023 signaling receptor activity
GO:0043149 stress fiber assembly
GO:0043235 receptor complex
GO:0045335 phagocytic vesicle
GO:0070062 extracellular exosome
GO:0090136 epithelial cell-cell adhesion

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR002035 von Willebrand factor, type ADomainDomain
IPR002369 Integrin beta subunit, VWA domainDomainDomain
IPR012896 Integrin beta subunit, tailDomainDomain
IPR014836 Integrin beta subunit, cytoplasmic domainDomainDomain
IPR015812 Integrin beta subunitFamilyFamily
IPR016201 PSI domainDomainDomain
IPR027067 Integrin beta-5 subunitFamilyFamily
IPR032695 Integrin domain superfamilyFamilyHomologous superfamily
IPR033760 Integrin beta N-terminalDomainDomain
IPR036349 Integrin beta tail domain superfamilyFamilyHomologous superfamily
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily
IPR040622 Integrin beta, epidermal growth factor-like domain 1DomainDomain

Diseases

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Interactions

71 interactions

InteractorPartnerSourcesPublicationsLink
ITB5_HUMANEPS8_HUMANHPRD, MINT12606711 details
ITB5_HUMANTNS2_HUMANHPRD, MINT12606711 details
ITB5_HUMANPDIA3_HUMANBioGRID, MINT17170699 details
ITB5_HUMANANGL4_HUMANIntAct21397862 details
ITB5_HUMANEWS_HUMANBioGRID, IntAct21988832 details
ITB5_HUMANSRSF9_HUMANBioGRID, IntAct21988832 details
ITB5_HUMANMYO10_HUMANHPRD, MINT15156152 21642953 details
ITB5_HUMANFDFT_HUMANBioGRID, IntAct23414517 details
ITB5_HUMANG3P_HUMANBioGRID, IntAct23414517 details
ITB5_HUMANGON4L_HUMANBioGRID, IntAct23414517 details
ITB5_HUMANMYPC2_HUMANBioGRID, IntAct23414517 details
ITB5_HUMANTAF1_HUMANBioGRID, IntAct23414517 details
ITB5_HUMANTITIN_HUMANBioGRID, IntAct23414517 details
ITB5_HUMANFRMD5_HUMANMINT25448675 details
ITB5_HUMANKR109_HUMANBioGRID, IntAct25416956 32296183 details
ITB5_HUMANFBLN4_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANKRT34_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANNT2NC_HUMANBioGRID, IntAct25416956 32296183 details
ITB5_HUMANFHL3_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANAPBP2_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANKR107_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANKR108_HUMANBioGRID, IntAct25416956 32296183 details
ITB5_HUMANCRTP1_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANKRA57_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANKRA11_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANKRA32_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANZN655_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANMTUS2_HUMANBioGRID, IntAct25416956 32296183 details
ITB5_HUMANK1H1_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANGOGA2_HUMANBioGRID, IntAct32296183 details
ITB5_HUMANTRI63_HUMANBioGRID, IntAct31391242 details
ITB5_HUMANTRI55_HUMANBioGRID, IntAct31391242 details
ITB5_HUMANANXA5_HUMANBioGRID, HPRD12769841 details
ITB5_HUMANFAK1_HUMANBioGRID11927607 15673687 details
ITB5_HUMANCCN1_HUMANBioGRID, HPRD11287419 details
ITB5_HUMANPAK4_HUMANBioGRID, HPRD12356872 details
ITB5_HUMANPPARD_HUMANBioGRID15604093 details
ITB5_HUMANSNTA1_HUMANBioGRID15123239 details
ITB5_HUMANEHMT2_HUMANBioGRID25416956 details
ITB5_HUMANK1C40_HUMANBioGRID25416956 details
ITB5_HUMANNT2NA_HUMANBioGRID25416956 32296183 details
ITB5_HUMANOSTP_HUMANBioGRID7592829 details
ITB5_HUMANZBT17_HUMANBioGRID, HPRD12356872 details
ITB5_HUMANSTAB2_HUMANBioGRID22566688 details
ITB5_HUMANKRA13_HUMANBioGRID32296183 details
ITB5_HUMANFHL2_HUMANHPRD16355270 details
ITB5_HUMANFLNA_HUMANHPRD16355270 details
ITB5_HUMANPALLD_HUMANHPRD16355270 details
ITB5_HUMANRACK1_HUMANHPRD9442085 details
ITB5_HUMANITAV_HUMANBioGRID, HPRD, IntAct12844492 1694173 7689573 details
ITB5_HUMANTLN2_HUMANMINT25448675 details
ITB5_HUMANFERM2_HUMANMINT25448675 details
ITB5_HUMANACE2_HUMANIntAct22523556 details
ITB5_HUMANACE_HUMANIntAct22523556 details
ITB5_HUMANCENPR_HUMANBioGRID, HPRD10579726 details
ITB5_HUMANITA3_HUMANBioGRID16878156 details
ITB5_HUMANEPHA2_HUMANBioGRID23874206 details
ITB5_HUMANITA5_HUMANBioGRID, HPRD11462216 22470492 7592829 details
ITB5_HUMANMYPR_HUMANBioGRID12196561 details
ITB5_HUMANADAM9_HUMANBioGRID16373656 details
ITB5_HUMANTIMD4_HUMANBioGRID30451988 details
ITB5_HUMANFINC_HUMANBioGRID30451988 details
ITB5_HUMANITB5_HUMANHPRD12606711 details
ITB5_HUMANLTBP1_HUMANHPRD12358597 details
ITB5_HUMANTLN1_HUMANHPRD12606711 details
ITB5_HUMANP2RY2_HUMANHPRD11331301 details
ITB5_HUMANDAB2_HUMANHPRD12606711 details
ITB5_HUMANLTBP3_HUMANHPRD12358597 details
ITB5_HUMANDOK1_HUMANHPRD12606711 details
ITB5_HUMANDAB1_HUMANHPRD12606711 details
ITB5_HUMANNUMB_HUMANHPRD12606711 details