Entity Details

Primary name EPOR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP19235
EntryNameEPOR_HUMAN
FullNameErythropoietin receptor
TaxID9606
Evidenceevidence at protein level
Length508
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesEPOR

GO terms

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GOName
GO:0004900 erythropoietin receptor activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0007420 brain development
GO:0007507 heart development
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016607 nuclear speck
GO:0042802 identical protein binding
GO:0046579 positive regulation of Ras protein signal transduction
GO:0046697 decidualization

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR003528 Long hematopoietin receptor, single chain, conserved siteSiteConserved site
IPR003961 Fibronectin type IIIDomainDomain
IPR009167 Erythropoietin receptorFamilyFamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015152 Growth hormone/erythropoietin receptor, ligand bindingDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00012 Darbepoetin alfaDrugbankbiotech
DB00016 ErythropoietinDrugbankbiotech
DB07637 DibromotyrosineDrugbanksmall molecule
DB08894 PeginesatideDrugbankbiotech
DB09107 Methoxy polyethylene glycol-epoetin betaDrugbankbiotech

Interactions

50 interactions

InteractorPartnerSourcesPublicationsLink
EPOR_HUMANSHIP1_HUMANBioGRID, HPRD, IntAct, MINT10660611 15644415 details
EPOR_HUMANPLCG2_HUMANHPRD, IntAct15644415 15953601 details
EPOR_HUMANSOCS2_HUMANBioGRID, HPRD, MINT11781573 15644415 16675548 16961462 details
EPOR_HUMANCISH_HUMANBioGRID, HPRD, MINT11781573 15644415 16961462 28038963 7796808 9774439 details
EPOR_HUMANPTN6_HUMANBioGRID, HPRD, MINT7228577 7528537 7528577 7889566 details
EPOR_HUMANEPO_HUMANBioGRID, DIP, HPRD, IntAct10318834 15358619 17327410 28514442 29997244 9774108 9808045 details
EPOR_HUMANPTN1_HUMANMINT14527337 details
EPOR_HUMANPTPRC_HUMANIntAct19167335 details
EPOR_HUMANPTPRG_HUMANIntAct19167335 details
EPOR_HUMANPTPRB_HUMANIntAct19167335 details
EPOR_HUMANPTPRJ_HUMANIntAct19167335 details
EPOR_HUMANPTPRO_HUMANIntAct19167335 details
EPOR_HUMANSOCS3_HUMANBioGRID, HPRD, MINT10882725 12027890 details
EPOR_HUMANEPOR_HUMANDIP, HPRD, IntAct16116438 21058338 8662530 9974392 details
EPOR_HUMANRACK1_HUMANBioGRID, HPRD12960323 details
EPOR_HUMANJAK2_HUMANBioGRID, HPRD11779507 12441334 14982882 8343951 details
EPOR_HUMANP85A_HUMANBioGRID, HPRD12506011 15644415 24113870 7559499 9162069 details
EPOR_HUMANLYN_HUMANBioGRID, HPRD9573010 details
EPOR_HUMANGNAI1_HUMANBioGRID, HPRD12538595 details
EPOR_HUMANGRB2_HUMANBioGRID, HPRD7534299 8647802 9129019 details
EPOR_HUMANPTN11_HUMANBioGRID, HPRD7534299 8639815 details
EPOR_HUMANGRAP_HUMANBioGRID, HPRD8647802 details
EPOR_HUMANCRKL_HUMANBioGRID, HPRD11443118 9129019 9344843 details
EPOR_HUMANSTA5A_HUMANBioGRID, HPRD10374881 15644415 8977232 details
EPOR_HUMANPLCG1_HUMANBioGRID, HPRD15329338 15644415 15953601 details
EPOR_HUMANSH2B2_HUMANBioGRID, HPRD10374881 details
EPOR_HUMANVHL_HUMANBioGRID26846855 details
EPOR_HUMANEGLN3_HUMANBioGRID26846855 details
EPOR_HUMANELOC_HUMANBioGRID26846855 details
EPOR_HUMANELOB_HUMANBioGRID26846855 details
EPOR_HUMANSTA5B_HUMANHPRD15644415 8977232 details
EPOR_HUMANATX2L_HUMANBioGRID, HPRD, UniProt11784712 details
EPOR_HUMANVAV_HUMANBioGRID, HPRD9162069 details
EPOR_HUMANIRS2_HUMANBioGRID, HPRD9334184 details
EPOR_HUMANSHC1_HUMANBioGRID, HPRD8400282 details
EPOR_HUMANKSYK_HUMANBioGRID, HPRD9852052 details
EPOR_HUMANFBW1A_HUMANBioGRID17327410 details
EPOR_HUMANNOSIP_HUMANBioGRID12746455 details
EPOR_HUMANCBL_HUMANBioGRID, HPRD10374881 11443118 details
EPOR_HUMANSRC_HUMANBioGRID21075308 details
EPOR_HUMANRON_HUMANBioGRID, HPRD14982882 details
EPOR_HUMANCUL2_HUMANBioGRID26846855 details
EPOR_HUMANGAB1_HUMANHPRD10455108 details
EPOR_HUMANIL3RB_HUMANHPRD12488507 details
EPOR_HUMANKIT_HUMANHPRD11124255 details
EPOR_HUMANKLK3_HUMANHPRD10374881 details
EPOR_HUMANMK01_HUMANHPRD12538595 details
EPOR_HUMANSCF_HUMANHPRD11124255 details
EPOR_HUMANMK03_HUMANHPRD12538595 details
EPOR_HUMANGAB2_HUMANHPRD10455108 details