Entity Details

Primary name SYTC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP26639
EntryNameSYTC_HUMAN
FullNameThreonine--tRNA ligase 1, cytoplasmic
TaxID9606
Evidenceevidence at protein level
Length723
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesTARS1

GO terms

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GOName
GO:0000049 tRNA binding
GO:0004829 threonine-tRNA ligase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006418 tRNA aminoacylation for protein translation
GO:0006435 threonyl-tRNA aminoacylation
GO:0008270 zinc ion binding
GO:0042802 identical protein binding
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)DomainDomain
IPR002320 Threonine-tRNA ligase, class IIaFamilyFamily
IPR004095 TGSDomainDomain
IPR004154 Anticodon-bindingDomainDomain
IPR006195 Aminoacyl-tRNA synthetase, class IIDomainDomain
IPR012675 Beta-grasp domain superfamilyFamilyHomologous superfamily
IPR012676 TGS-likeFamilyHomologous superfamily
IPR012947 Threonyl/alanyl tRNA synthetase, SADDomainDomain
IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamilyFamilyHomologous superfamily
IPR033728 Threonine-tRNA ligase catalytic core domainDomainDomain
IPR036621 Anticodon-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00156 ThreonineDrugbanksmall molecule