Entity Details

Primary name PEX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP28328
EntryNamePEX2_HUMAN
FullNamePeroxisome biogenesis factor 2
TaxID9606
Evidenceevidence at protein level
Length305
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesPEX2

GO terms

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GOName
GO:0000038 very long-chain fatty acid metabolic process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0005778 peroxisomal membrane
GO:0005779 integral component of peroxisomal membrane
GO:0005829 cytosol
GO:0006635 fatty acid beta-oxidation
GO:0007031 peroxisome organization
GO:0008104 protein localization
GO:0016020 membrane
GO:0016558 protein import into peroxisome matrix
GO:0016567 protein ubiquitination
GO:0016593 Cdc73/Paf1 complex
GO:0031648 protein destabilization
GO:0045046 protein import into peroxisome membrane
GO:0046872 metal ion binding
GO:0048147 negative regulation of fibroblast proliferation
GO:0050680 negative regulation of epithelial cell proliferation

Subcellular Location

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Subcellular Location
Peroxisome membrane

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR006845 Pex, N-terminalDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR018957 Zinc finger, C3HC4 RING-typeDomainDomain

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
PEX2_HUMANERG28_HUMANBioGRID, HPRD, IntAct16169070 details
PEX2_HUMANTLE1_HUMANBioGRID, HPRD, IntAct16169070 details
PEX2_HUMANPEX19_HUMANMINT20531392 details
PEX2_HUMANPEX10_HUMANBioGRID, HPRD10837480 details
PEX2_HUMANA4_HUMANBioGRID21832049 details