Entity Details

Primary name PURA2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30520
EntryNamePURA2_HUMAN
FullNameAdenylosuccinate synthetase isozyme 2
TaxID9606
Evidenceevidence at protein level
Length456
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesADSS2

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0002376 immune system process
GO:0004019 adenylosuccinate synthase activity
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006167 AMP biosynthetic process
GO:0006531 aspartate metabolic process
GO:0009168 purine ribonucleoside monophosphate biosynthetic process
GO:0014074 response to purine-containing compound
GO:0042301 phosphate ion binding
GO:0044208 'de novo' AMP biosynthetic process
GO:0046040 IMP metabolic process
GO:0060359 response to ammonium ion
GO:0070062 extracellular exosome
GO:0071257 cellular response to electrical stimulus

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion

Domains

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DomainNameCategoryType
IPR001114 Adenylosuccinate synthetaseFamilyFamily
IPR018220 Adenylosuccinate synthase, GTP-binding siteSiteBinding site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR027529 Adenylosuccinate synthetase isozyme 2, chordatesFamilyFamily
IPR033128 Adenylosuccinate synthase, active siteSiteActive site
IPR042109 Adenylosuccinate synthetase, domain 1FamilyHomologous superfamily
IPR042110 Adenylosuccinate synthetase, domain 2FamilyHomologous superfamily
IPR042111 Adenylosuccinate synthetase, domain 3FamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00128 Aspartic acidDrugbanksmall molecule
DB00787 AcyclovirDrugbanksmall molecule
DB05540 AlanosineDrugbanksmall molecule

Interactions

4 interactions