Entity Details

Primary name GRIA4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48058
EntryNameGRIA4_HUMAN
FullNameGlutamate receptor 4
TaxID9606
Evidenceevidence at protein level
Length902
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesGRIA4

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0004970 ionotropic glutamate receptor activity
GO:0004971 AMPA glutamate receptor activity
GO:0005886 plasma membrane
GO:0007215 glutamate receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0015276 ligand-gated ion channel activity
GO:0030666 endocytic vesicle membrane
GO:0032281 AMPA glutamate receptor complex
GO:0038023 signaling receptor activity
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0045211 postsynaptic membrane
GO:1903561 extracellular vesicle
GO:2000310 regulation of NMDA receptor activity

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR001320 Ionotropic glutamate receptorDomainDomain
IPR001508 Ionotropic glutamate receptor, metazoaFamilyFamily
IPR001828 Receptor, ligand binding regionDomainDomain
IPR019594 Ionotropic glutamate receptor, L-glutamate and glycine-binding domainDomainDomain
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule
DB00237 ButabarbitalDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule
DB04982 TalampanelDrugbanksmall molecule
DB05047 CX-717Drugbanksmall molecule
DB13146 Fluciclovine (18F)Drugbanksmall molecule