Entity Details

Primary name PAPOA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51003
EntryNamePAPOA_HUMAN
FullNamePoly(A) polymerase alpha
TaxID9606
Evidenceevidence at protein level
Length745
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesPAPOLA

GO terms

Show/Hide Table
GOName
GO:0000287 magnesium ion binding
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0004652 polynucleotide adenylyltransferase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006369 termination of RNA polymerase II transcription
GO:0006378 mRNA polyadenylation
GO:0030145 manganese ion binding
GO:0031124 mRNA 3'-end processing
GO:0031440 regulation of mRNA 3'-end processing
GO:0043631 RNA polyadenylation

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR002934 Polymerase, nucleotidyl transferase domainDomainDomain
IPR007010 Poly(A) polymerase, RNA-binding domainDomainDomain
IPR007012 Poly(A) polymerase, central domainDomainDomain
IPR011068 Nucleotidyltransferase, class I-like, C-terminalFamilyHomologous superfamily
IPR014492 Poly(A) polymeraseFamilyFamily
IPR043519 Nucleotidyltransferase superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB01860 Cordycepin TriphosphateDrugbanksmall molecule
DB02153 3-sulfino-L-alanineDrugbanksmall molecule
DB03896 Triphosphoric acidDrugbanksmall molecule