Entity Details

Primary name RING1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ06587
EntryNameRING1_HUMAN
FullNameE3 ubiquitin-protein ligase RING1
TaxID9606
Evidenceevidence at protein level
Length406
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesRING1

GO terms

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GOName
GO:0000151 ubiquitin ligase complex
GO:0001739 sex chromatin
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0009952 anterior/posterior pattern specification
GO:0016607 nuclear speck
GO:0031519 PcG protein complex
GO:0035102 PRC1 complex
GO:0035518 histone H2A monoubiquitination
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0048593 camera-type eye morphogenesis
GO:0061630 ubiquitin protein ligase activity
GO:0070317 negative regulation of G0 to G1 transition
GO:0097027 ubiquitin-protein transferase activator activity

Subcellular Location

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Subcellular Location
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR032443 RAWUL domainDomainDomain
IPR042741 RING1 , RING finger, HC subclassDomainDomain
IPR043540 E3 ubiquitin-protein ligase RING1/RING2FamilyFamily

Diseases

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Interactions

67 interactions

InteractorPartnerSourcesPublicationsLink
RING1_HUMANRYBP_HUMANBioGRID, HPRD, IntAct, MINT, UniProt10369680 16189514 16943429 17070805 22325352 24981860 25416956 26186194 27705803 28514442 30217970 32296183 details
RING1_HUMANP55G_HUMANBioGRID, IntAct18624398 details
RING1_HUMANUB2D2_HUMANBioGRID, IntAct19549727 29643511 32296183 details
RING1_HUMANUB2D1_HUMANBioGRID, IntAct19549727 19956605 32296183 details
RING1_HUMANUB2D3_HUMANBioGRID, IntAct19549727 details
RING1_HUMANUB2E1_HUMANBioGRID, IntAct19549727 28073915 details
RING1_HUMANUB2E2_HUMANBioGRID, IntAct19549727 details
RING1_HUMANUB2E3_HUMANBioGRID, IntAct19549727 details
RING1_HUMANUB2D4_HUMANBioGRID, IntAct19549727 32296183 details
RING1_HUMANUBP7_HUMANBioGRID, IntAct, MINT20601937 20800574 26496610 details
RING1_HUMANUBP11_HUMANBioGRID, MINT20601937 details
RING1_HUMANBMI1_HUMANBioGRID, HPRD, IntAct, MINT, UniProt15386022 16359901 16751658 19451220 19636380 20601937 22325352 22493164 22897849 24457600 24981860 25416956 27705803 29402932 32296183 9199346 9858531 details
RING1_HUMANPCGF2_HUMANBioGRID, IntAct, MINT, UniProt17936708 19636380 20601937 21516116 22325352 22493164 24981860 27705803 28514442 32296183 details
RING1_HUMANYAF2_HUMANBioGRID, IntAct, MINT21516116 22325352 24981860 25416956 27684187 27705803 28514442 32296183 details
RING1_HUMANFBX38_HUMANBioGRID, IntAct21988832 details
RING1_HUMANCBX4_HUMANBioGRID, HPRD, IntAct, MINT, UniProt21282530 22078878 22325352 24981860 26496610 27705803 30317550 9199346 9858531 details
RING1_HUMANCBX6_HUMANBioGRID, IntAct, MINT, UniProt21282530 22325352 24981860 27705803 details
RING1_HUMANCBX7_HUMANBioGRID, HPRD, IntAct, UniProt14647293 19636380 21282530 27705803 details
RING1_HUMANCBX8_HUMANBioGRID, HPRD, IntAct, MINT, UniProt10825164 21282530 24981860 25416956 26496610 27705803 32296183 details
RING1_HUMANRING2_HUMANBioGRID, HPRD, IntAct, MINT, UniProt12183370 15386022 16359901 16943429 21596310 22325352 24457600 24981860 26496610 details
RING1_HUMANPCGF1_HUMANBioGRID, IntAct, MINT, UniProt16943429 22325352 22493164 24981860 26687479 27505670 27705803 details
RING1_HUMANPCGF3_HUMANBioGRID, IntAct, MINT22325352 22493164 24981860 27705803 32296183 details
RING1_HUMANPCGF6_HUMANBioGRID, IntAct, MINT12167161 22325352 22493164 24981860 27705803 28514442 32296183 details
RING1_HUMANPCGF5_HUMANBioGRID, IntAct, MINT22325352 22493164 24981860 26186194 27705803 28514442 32296183 details
RING1_HUMANE2F6_HUMANBioGRID, HPRD, IntAct, MINT11171983 24981860 27705803 details
RING1_HUMANCBX2_HUMANBioGRID, IntAct, MINT10369680 22325352 24981860 27705803 details
RING1_HUMANIKBD_HUMANBioGRID, IntAct32296183 details
RING1_HUMANUBE2K_HUMANBioGRID, IntAct19549727 32296183 32814053 details
RING1_HUMANZIM3_HUMANBioGRID, IntAct32296183 details
RING1_HUMANP53_HUMANBioGRID, IntAct22907436 29187402 details
RING1_HUMANTRI55_HUMANBioGRID, IntAct31391242 details
RING1_HUMANCASP6_HUMANIntAct32814053 details
RING1_HUMANLAMP2_HUMANIntAct32814053 details
RING1_HUMANSPRE1_HUMANIntAct32814053 details
RING1_HUMANRING1_HUMANBioGRID, HPRD19956605 9858531 details
RING1_HUMANA4_HUMANBioGRID21832049 details
RING1_HUMANFHL1_HUMANBioGRID, HPRD14999091 15710417 details
RING1_HUMANH31T_HUMANBioGRID20850016 details
RING1_HUMANERG_HUMANBioGRID27626314 details
RING1_HUMANBASI_HUMANBioGRID28832687 details
RING1_HUMANPTEN_HUMANBioGRID31685992 details
RING1_HUMANTRI63_HUMANBioGRID31391242 details
RING1_HUMANH2A1B_HUMANBioGRID29386386 details
RING1_HUMANOGT1_HUMANBioGRID32994395 details
RING1_HUMANRNZ2_HUMANHPRD9199346 details
RING1_HUMANUBC_HUMANMINT20601937 details
RING1_HUMANCBX3_HUMANBioGRID, IntAct, MINT12004135 24981860 27705803 details
RING1_HUMANPHC1_HUMANBioGRID, HPRD, IntAct, MINT22325352 24981860 27705803 28514442 9199346 details
RING1_HUMANWDR5_HUMANBioGRID, IntAct, MINT22325352 24981860 27705803 details
RING1_HUMANE2F1_HUMANBioGRID, IntAct11583618 27705803 details
RING1_HUMANRB_HUMANBioGRID, HPRD11583618 details
RING1_HUMANCENPA_HUMANBioGRID15009096 details
RING1_HUMANTERF1_HUMANBioGRID20811636 details
RING1_HUMANTERF2_HUMANBioGRID20811636 details
RING1_HUMANTOP2A_HUMANBioGRID19956605 details
RING1_HUMANSMRCD_HUMANBioGRID21549307 details
RING1_HUMANZFP42_HUMANBioGRID21530438 details
RING1_HUMANTYY2_HUMANBioGRID21530438 details
RING1_HUMANTYY1_HUMANBioGRID16624538 details
RING1_HUMANSNAI1_HUMANBioGRID24903147 details
RING1_HUMANEED_HUMANBioGRID24457600 details
RING1_HUMANUBR5_HUMANBioGRID27647897 details
RING1_HUMANNOS2_HUMANBioGRID27623813 details
RING1_HUMANMN1_HUMANBioGRID31839203 details
RING1_HUMANMYCN_HUMANBioGRID31856871 details
RING1_HUMANSMG7_HUMANBioGRID29395067 details
RING1_HUMANTULP3_HUMANBioGRID33187986 details