Entity Details
| Primary name |
SKOR2_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q2VWA4 |
| EntryName | SKOR2_HUMAN |
| FullName | SKI family transcriptional corepressor 2 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 1001 |
| SequenceStatus | complete |
| DateCreated | 2008-05-20 |
| DateModified | 2021-06-02 |
GO terms
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| GO | Name |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0005634 | nucleus |
| GO:0005667 | transcription regulator complex |
| GO:0005737 | cytoplasm |
| GO:0006355 | regulation of transcription, DNA-templated |
| GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway |
| GO:0030514 | negative regulation of BMP signaling pathway |
| GO:0046332 | SMAD binding |
| GO:1990837 | sequence-specific double-stranded DNA binding |
Subcellular Location
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| Subcellular Location |
| Cytoplasm |
| Nucleus |
Domains
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| Domain | Name | Category | Type |
| IPR003380 | SKI/SNO/DAC domain | Domain | Domain |
| IPR009061 | Putative DNA-binding domain superfamily | Family | Homologous superfamily |
| IPR010919 | SAND-like domain superfamily | Family | Homologous superfamily |
| IPR014890 | c-SKI SMAD4-binding domain | Domain | Domain |
| IPR023216 | Transcription regulator SKI/SnoN | Family | Family |
| IPR028376 | SKI family transcriptional corepressor 2 | Family | Family |
| IPR037000 | Ski-like, DNA-binding domain superfamily | Family | Homologous superfamily |
Interactions
2 interactions